Kidney Week

Abstract: TH-PO0704

Renal Resistive Index in Severe Preeclampsia: Correlation with Glomerular Filtration Rate and Diagnostic Accuracy for AKI

Session Information

• AKI: Prevention, Diagnostics, and Management
  October 22, 2026 | Location: Exhibit Hall A, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Acute Kidney Injury

• 101 AKI: Epidemiology, Risk Factors, and Prevention

Authors

• Alcantar Vallin, Maria de la Luz, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Maria de la Luz Alcantar Vallin, MD

• Zaragoza, Jose Jesus, Hospital Q+, Queretaro, Mexico

Jose Jesus Zaragoza, MD

• Chavez, Jonathan, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Jonathan Chavez, MD, PhD

• Navarro Blackaller, Guillermo, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Guillermo Navarro Blackaller, MD

• Medina, Ramon, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Ramon Medina, MD

• Martínez Gallardo González, Alejandro, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Alejandro Martínez Gallardo González

• Renoirte, Karina, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Karina Renoirte, PhD

• Mendoza Gaitán, Héctor Eduardo, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Héctor Eduardo Mendoza Gaitán, MD

• Gómez, Juan Alberto, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Juan Alberto Gómez, MD

• Arizaga Napoles, Manuel, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico

Manuel Arizaga Napoles, MD

• Cruz Aragon, Fernando, Universidad de Guadalajara, Guadalajara, Jal., Mexico

Fernando Cruz Aragon, MD

Background

This study aimed to evaluate the diagnostic performance of RRI for predicting Acute Kidney Injury (AKI) and glomerular filtration rate (GFR) in patients with severe preeclampsia.

Methods

This observational study included 22 patients admitted with severe preeclampsia. RRI was measured at admission. AKI was defined and staged according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Receiver Operating Characteristic (ROC) curve analysis was used to assess RRI's ability to predict AKI and measured creatinine clearance

Results

Of the 22 patients, 9 (40.9%) developed AKI. Patients who developed AKI had significantly higher admission RRI values compared to those who did not (mean 0.75 ± 0.19 vs. 0.45 ± 0.13, respectively; p<0.001). The area under the ROC curve for RRI predicting AKI was 0.87 (95% CI, 0.65–0.97). In the multivariate linear regression analysis, RRI showed a borderline significant negative association with adjusted GFR (β = -112.67; p=0.095), though the overall model was not statistically significant (p=0.23).

Conclusion

The Renal Resistive Index measured at ICU admission is a promising, noninvasive predictor of AKI in patients with severe preeclampsia, demonstrating good diagnostic accuracy with high specificity at an optimal cut-off.