ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

Abstract: TH-PO0882

Ultrasound Markers of Fluid Overload in Patients on Hemodialysis Compared with Bioimpedance Spectroscopy

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Arizaga Napoles, Manuel, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Chavez, Jonathan, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Cruz Aragon, Fernando, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • De la Torre De la Vega, Ixchel, Universidad de Guadalajara, Guadalajara, Jal., Mexico
  • Martínez Aguilar, Alma Isela, Universidad de Guadalajara, Guadalajara, Jal., Mexico
  • Tanaka-Gutiérrez, Jarumi Andrea, Universidad de Guadalajara, Guadalajara, Jal., Mexico
  • Medina, Ramon, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Alcantar Vallin, Maria de la Luz, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Martínez Gallardo González, Alejandro, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Mendoza Gaitán, Héctor Eduardo, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Renoirte, Karina, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Abundis Mora, Gabriela Jazmín, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Navarro Blackaller, Guillermo, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
  • Gómez, Juan Alberto, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico
Background

Fluid overload (FO) in hemodialysis (HD) patients associates to increased mortality. Bioimpedance spectroscopy (BIS) is an objective method to detect FO and is used in many parts of the world. Ultrasound imaging of lungs (LUS) and inferior vena cava diameter (IVCD) for the detection of FO has also been proposed for the diagnosis of FO. We investigated diagnostic performance of FO by use of LUS, IVCD, in reference to results obtained by BIS.

Methods

We included prevalent HD patients in this cross-sectional study and analyzed the association between FO diagnosed by clinical assessment, BIS, LUS by assessment of B-lines, and IVCD; evaluated diagnostic performance with different cut-offs, and further investigated the association of intradialytic changes of the markers with ultrafiltration (UF) volume removed.

Results

We studied 78 patients (age 37+/-SD, 41% female, 65% with FO as per BCM) between 2022 and 2023. A lower number of B-lines number had fewer frequency of FO, and defining a cutoff of ≥2 B lines as being fluid overloaded, had a sensitivity of 90% (CI 82-98%), and a specificity of 75% (CI 64-86%), a positive predictive value 56% (CI 42-70%), and the negative predictive value of 93% (CI 80-100%) in diagnosing FO as defined by BCM. Defining a IVCD of 1.75 cm as fluid overloaded resulted in an AUC of 0.84. Both LUS score and IVCD, correlated with the UF volume with a correlation coefficient of 0.91. I would suggest a uniform presentation of diagnostic performance. I.e. ROC AUC for IVCD and US

Conclusion

While differences in diagnostic performance were observed, the use of handheld ultrasound devices allowed by assessment of LUS and IVCD to diagnose FO.