ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

Abstract: FR-PO0021

Effects of Macroeconomic Indicators on Kidney Transplant Awareness in the United States: A SARIMAX Analysis of Google Search Trends, 2004-2025

Session Information

Category: Artificial Intelligence, Digital Health, and Data Science

  • 300 Artificial Intelligence, Digital Health, and Data Science

Authors

  • Kookanok, Chutawat, Interfaith Medical Center, New York, New York, United States
  • Poochanasri, Methavee, Phramongkutklao Hospital, Bangkok, Bangkok, Thailand
  • Kulthamrongsri, Narathorn, University of Hawai'i System, Honolulu, Hawaii, United States
  • Yongkiatkan, Panchanit, University of California Irvine, Irvine, California, United States
  • Sackey, Jeffrey Afrah, Interfaith Medical Center, New York, New York, United States
  • Phichedwanichskul, Kitinan, Phramongkutklao Hospital, Bangkok, Bangkok, Thailand
  • Tangprasittichok, Nathasith, Phramongkutklao Hospital, Bangkok, Bangkok, Thailand
  • Aiumtrakul, Noppawit, Mayo Clinic Minnesota, Rochester, Minnesota, United States
Background

Kidney transplantation(KT) remains the optimal treatment for kidney failure; however, transplant volumes are influenced by social and economic conditions. This study evaluates the performance of a Seasonal Autoregressive Integrated Moving Average with Exogenous Regressors(SARIMAX) model in forecasting KT searching volumes and examining the impact of economic indicators on transplant trends.

Methods

The monthly Google Search Index(0–100) for the term “Kidney Transplant” and FRED(Federal Reserve Economic Data) economic indicators(Table 1) were analyzed from January 2004 to August 2025. Time-series decomposition, auto.arima function in R program and data training procedure were used to guide appropriate model selection.

Results

The lowest monthly search volume(score = 32) occurred in December 2011, while the highest search volume was observed in July 2025(score = 100)(Fig. 1). Time-series decomposition confirmed a upward trend and seasonal patterns(Fig. 1). The final model, selected via auto.arima demonstrated performance with MAE = 3.778, RMSE = 5.711, MAPE = 7.34%, and no autocorrelation(ACF1 < 0.01; Ljung–Box test p-value = 0.138). Unemployment and Industrial Production were identified as negative predictors, whereas Disposable Personal Income showed a positive association(Table 1). The KT prediction plot is shown in Fig. 2.

Conclusion

SARIMAX model effectively predicted KT search volume. Increased unemployment and decreased industrial production were associated with reduced search activity, while increased real disposable income was linked to higher engagement. Integrating these indicators strengthens forecasting accuracy, helping health systems anticipate resource needs and potential economic barriers to patient access.

Table 1. Coefficients of Macroeconomic Predictors in the SARIMAX Model.
FactorCoefficientStandard ErrorT-Statistic
Unemployment Rate (UNRATE)-2.78550.5955-4.678
Industrial Production (INDPRO)-0.66250.2908-2.278
Disposable Personal Income (DSPIC96)0.00360.00066
10-year Treasury Yield (GS10)0.94260.91361.032