Abstract: FR-PO1028
Exploring the Prevalence and Clinical Associations of Intradialytic Hypertension in Adults Receiving Maintenance Hemodialysis
Session Information
- Hemodialysis: Clinical Challenges, Patient-Centered Outcomes, and Quality of Life
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Kathiresan, Lalit, University of Leicester Department of Cardiovascular Sciences, Leicester, England, United Kingdom
- Quann, Niamh, University of Leicester Department of Cardiovascular Sciences, Leicester, England, United Kingdom
- March, Daniel Scott, University of Leicester Department of Cardiovascular Sciences, Leicester, England, United Kingdom
- Burton, James, University of Leicester Department of Cardiovascular Sciences, Leicester, England, United Kingdom
- Hull, Katherine Leigh, University of Leicester Department of Cardiovascular Sciences, Leicester, England, United Kingdom
Background
Intradialytic hypertension is associated with increased mortality and hospitalisation, yet it is poorly recognised. This study aimed to determine the prevalence of intradialytic hypertension in the Leicester Renal Network and associated clinical characteristics.
Methods
3 dialysis units were screened for intradialytic hypertension; an increase in SBP >10mmHg ≥3 consecutive HD sessions. Patients consented to complete the Montreal Cognitive Assessment (MoCA), Integrated Patient Outcome Score-Renal (IPOS-Renal), Low Physical Activity Questionnaire and review of medical records in this cross-sectional study. 2 groups of 25 patients were recruited, patients with intradialytic hypertension and matched control patients. Statistical testing: Mann-Whitney U-tests and backwards stepwise logistic regression.
Results
11.6% (51/438) of patients screened experienced intradialytic hypertension. Baseline characteristics: intradialytic hypertension group (n=25) 57y (IQR 47-71y), 48% male (n=12), mean change in SBP during last 3 HD sessions +10mmHg (+/-17); control group (n=25) 62y (IQR 55-73y), 48% male (n=12), mean change in SBP during HD -13mmHg (+/-14). MoCA scores were significantly lower in the intradialytic hypertension group (22, IQR 17-25) than the control group (25, IQR 22-27), z=2.03, P=0.04. IPOS-Renal was lower in the intradialytic hypertension group (20, IQR 12-34) than the control group (30, IQR 16-42), z=1.28, P=0.2. Physical activity levels were similar in both groups. The intradialytic hypertension group spent more nights in hospital in the preceding 12 months compared to the control group (27, IQR 8-48, vs. 10, IQR 4-23), z=-1.17, P=0.24. Binomial logistic regression suggests that patients with intradialytic hypertension were more likely to have a history of heart failure and/or stroke (Table 1).
Conclusion
Over 10% of the dialysis population have intradialytic hypertension; predictors include history of stroke/heart failure. Intradialytic hypertension associates with lower cognitive scores. This reflects the importance of consistent BP management for dialysis patients as recommended in the UK Kidney Association guidelines.
Logistic regression for characteristics predicting presence of intradialytic hypertension
| Variable | Co-efficient (β) | Standard error | Odds ratio | Confidence interval |
| Constant | -0.452 | 0.342 | ||
| History of stroke/heart failure | 1.751 | 0.736 | 5.8 | 1.4 - 24.4 |