Abstract: TH-PO1016
Prediction Model and Evaluation of Donor eGFR/Recipient Body Surface Area (BSA) Ratio for Postoperative Graft Function Within One Year in Living Donor Kidney Transplantation
Session Information
- Transplantation: Clinical - Outcomes, Malignancy, and Pathology
October 22, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 2002 Transplantation: Clinical
Authors
- Li, Dingran, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
- Wu, Taihao, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
- Zhu, Yichen, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
- Zhang, Ai-hua, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
Background
Early graft function recovery is crucial for long term prognosis in Living donor kidney transplantation. Physiological evidence indicates that donor-recipient mismatch can influence graft function and long term outcomes. Thus, a simple composite index reflecting both donor filtration capacity and recipient metabolic demand is required.
Methods
Clinical data from donors and recipients undergoing living donor kidney transplantation were retrospectively analyzed. ROC and RCS were used to evaluate the predictive efficacy of this ratio for recipient graft function at 1 week, 1 month, 3 months, 6 months, and 12 months post-transplantation.
Results
The area under the ROC curve of the eGFR/BSA ratio for predicting graft dysfunction at one week, one month, three months, six months, and twelve months post-transplantation were 0.610, 0.680, 0.666, 0.636, and 0.751, respectively. RCS analysis revealed that when the ratio exceeded 55.9, the risk of graft dysfunction decreased significantly at 12 months post-transplantation.
Conclusion
Donor eGFR/Recipient BSA ratio is a simple and useful indicator for predicting graft function within one year after kidney transplantation, whcih is convenient to calculate and aids in perioperative management.
ROC of the eGFR/BSA for predicting recipient graft dysfunction at 1 week, 1 month, 3 months, 6 months, and 12 months.
Restricted cubic spline regression plot of eGFR/BSA versus recipient graft dysfunction at 12 months post-transplantation.
Funding
- Government Support – Non-U.S.