Abstract: SA-PO0474
Potential Effects of Close Follow-Up After Hospitalization on Use of Guideline-Directed Medical Therapy in Patients with Cardiorenal Metabolic Syndrome
Session Information
- CKM: Clinical - Screening, Population Management, Care Disparities, and Patient-Centered Outcomes
October 24, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Cardiovascular-Kidney-Metabolic Health
- 602 Cardiovascular-Kidney-Metabolic Health: Clinical
Authors
- Attallah, Raya, Kentucky Country Day School, Louisville, Kentucky, United States
- Attallah, Nizar M., Nephrology Associates of Kentuckiana, Louisville, Kentucky, United States
Background
Cardiorenal metabolic syndrome (CRMS) is a prevalent condition. Patients affected are at higher risk for hospitalization, complications and death. Both heart failure and chronic kidney disease (CKD) will worsen the outcome of each other. Utilization of guideline-directed medical therapy (GDMT) and close follow up (F/U) after discharge improve outcomes and survival in such patients. We aim in this study to analyze the effect of early F/U of CRMS patients after hospitalization on utilization of GDMT.
Methods
We performed a retrospective chart review of 364 patients who had CKD (stage 3b and 4), type 2 diabetes and cardiorenal syndrome (type 2 or type 4) who were hospitalized between July 1, 2022 and June 30, 2025 due to volume overload with a minimum F/U of 6 months after hospitalization. Baseline characteristics, medications and labs were collected at the time of discharge and compared with the data at the first F/U visit and at 6 months after discharge using appropriate parametric or non-parametric testing methods. Patients were included regardless of their ejection fraction (EF).
Results
Patients studied were hospitalized at least once with volume overload. 225 patients (62.1%) developed acute kidney injury during hospitalization. Diuretics were optimized during hospitalizations. 220 patients were males (60.4%). Mean length of stay was 5 (+2) days. Mean age was 68.2 (+6.1) years. Mean estimated GFR (eGFR) upon discharge was 29 ml/min. Mean eGFR at 6 months was 27 ml/min. 211 patients (58%) had reduced EF (less than 40%). Table 1 summarizes utilization of GDMT and readmission rates depending on how soon the patients were seen in the office (by a cardiologist, nephrologist or primary care provider) after discharge. Medications reconciliation and optimization were performed during the visits.
Conclusion
In this study, early and close follow up after hospital discharge in severe CRMS patients may increase utilization of GDMT and lower risk of rehospitalizations.
Table 1
| On Discharge* | F/U 3-7 days* | F/U 8-14 days* | F/U more than 14 days* | P value# | |
| Use of B blockers | 84.9 | 90.1 | 87.9 | 85.1 | 0.79 |
| Use of SGLT2 inhibitors | 20 | 29.9 | 26.9 | 18.1 | 0.045 |
| Use of RAAS inhibitors | 29.9 | 50 | 40.9 | 31.9 | 0.033 |
| Use of MRAs | 25 | 40.1 | 29.9 | 28 | 0.038 |
| Readmission at 6 months | 39 | 49.4 | 59.9 | 0.041 |
*Numbers represent percentages #P value less than 0.05 was statistically significant