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Kidney Week

Abstract: TH-PO0731

Clinical and Operational Determinants of CRRT Use: A Mixed-Methods Analysis

Session Information

Category: Acute Kidney Injury

  • 102 AKI: Clinical, Outcomes, and Trials

Authors

  • Neyra, Javier A., University of Alabama at Birmingham Health System, Birmingham, Alabama, United States
  • Yessayan, Lenar Tatios, University of Michigan, Ann Arbor, Michigan, United States
  • Echeverri, Jorge E., Vantive US Healthcare LLC, Deerfield, Illinois, United States
  • Murugan, Raghavan, University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Background

CRRT prescription and delivery vary across institutions. Identifying key clinical and operational drivers may enable improved access, consistency, and quality. A multidisciplinary advisory board was convened to capture experiential insights.

Methods

We conducted an explanatory mixed-methods study combining a pre-meeting survey with qualitative analysis of a live workshop involving a multiprofessional group of 15 U.S. CRRT experts (nephrologists, intensivists, and nurse leaders), focusing on CRRT stakeholder roles and workflows, program maturity and sustainability barriers, and strategies to enhance adoption of evidence-based practices and quality.

Results

CRRT utilization was influenced by patient acuity, volume and complexity, as well as institutional infrastructure such as staffing and equipment. Key barriers included limited time, budget, training, and administrative and financial support, along with insufficient process harmonization. Participants also reported gaps in data access and collection, poor CRRT-Electronic Health Records (EHR) interoperability, absence of standardized quality metrics, limited confidence in troubleshooting resolution, communication challenges at decision points, equipment and supply availability, and suboptimal device and consumable optimization. Opportunities for structural and process improvement are summarized in Table 1.

Conclusion

Optimal CRRT delivery relies on trained teams, clear roles, efficient workflows, and reliable resources. Standardized protocols, scalable competency programs, workflow simplification, and infrastructure support may improve CRRT consistency and quality across hospital settings.

Funding

  • Commercial Support – Vantive Health LLC