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Kidney Week

Abstract: SA-PO0467

Pharmacist-Clinician Collaboration to Optimize SGLT2 Inhibitor Prescribing in a Rural Veterans Affairs (VA) Primary Care Clinic: A Quality Improvement Initiative

Session Information

Category: Cardiovascular-Kidney-Metabolic Health

  • 602 Cardiovascular-Kidney-Metabolic Health: Clinical

Authors

  • Nelson, Laura Elizabeth, University of Iowa Health Care, Iowa City, Iowa, United States
  • Seright, Teresa J., US Department of Veterans Affairs, Washington, District of Columbia, United States
  • Clausen, Sonja R., US Department of Veterans Affairs, Washington, District of Columbia, United States
  • Miller, Karla L., VA Salt Lake City Health Care System, Salt Lake City, Utah, United States
  • Swee, Melissa L., University of Iowa Health Care, Iowa City, Iowa, United States
Background

Sodium glucose cotransporter 2 inhibitors (SGLT2i) reduce cardiovascular events and slow chronic kidney disease (CKD) progression in patients with type 2 diabetes (T2DM), cardiovascular disease (CVD), heart failure (HF), or CKD. Despite strong guideline support, uptake has lagged across many practice settings, including rural primary care. In April 2025, only 44.2% of eligible Veterans at a rural VA Community-Based Outpatient Clinic (CBOC) were prescribed an SGLT2i, below the national VA average of ~50%. To address this gap, we launched a 6-month pharmacist–clinician quality improvement initiative.

Methods

We applied a Lean Six Sigma framework among Veterans with T2DM and comorbid CVD, HF, or CKD. Root cause analysis identified three drivers of underutilization: 1) inconsistent EHR identification of eligible patients, 2) provider uncertainty about prescribing thresholds, and 3) absent pharmacist outreach. We deployed a multi-component intervention combining pharmacist–led panel review with proactive outreach, provider education on guidelines, and standardized EHR documentation templates. Monthly prescribing rates were tracked on a statistical process control (SPC) chart.

Results

Of 78 eligible Veterans identified, 55 were contacted by the pharmacist-clinician team and 41 (75%) initiated or reinitiated SGLT2i therapy. The SPC chart demonstrated special-cause variation, with prescribing rising from 44.2% (April 2025) to 71.8% (October 2025), exceeding the national VA average (~50%), reaching the upper control limit, and sustained above the centerline.

Conclusion

A pharmacist–clinician collaborative model meaningfully improved SGLT2i prescribing for high-risk Veterans in a rural VA primary care setting, closing an evidence-to-practice gap in a population with documented prescribing disparities. Next steps will extend this model to other underutilized guideline-directed therapies.

Funding

  • Veterans Affairs Support