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Kidney Week

Abstract: FR-PO0044

Exploring Use of a Cloud-Based mHealth Platform in a Young Adult Nephrology Clinic

Session Information

Category: Artificial Intelligence, Digital Health, and Data Science

  • 300 Artificial Intelligence, Digital Health, and Data Science

Authors

  • McAnallen, Susan Marie, St. James's Hospital, Dublin, Ireland
  • Murphy, Mairead M., St. James's Hospital, Dublin, Ireland
  • Ni Cathain, Dearbhail, St. James's Hospital, Dublin, Ireland
  • Reidy, Donnchadh, St. James's Hospital, Dublin, Ireland
  • Bowden, Adam, St. James's Hospital, Dublin, Ireland
  • Brennan, Laura, St. James's Hospital, Dublin, Ireland
  • Sreedharan, Shena Rai, Trinity College Dublin School of Medicine, Dublin, Leinster, Ireland
  • Jackson, Cliodhna Frances, Trinity College Dublin School of Medicine, Dublin, Leinster, Ireland
  • Dhele, Amisha, Trinity College Dublin School of Medicine, Dublin, Leinster, Ireland
  • Aggarwal, Rahul, Trinity College Dublin School of Medicine, Dublin, Leinster, Ireland
  • Elkerany, Waleed El Said Gad, St. James's Hospital, Dublin, Ireland
  • Kennedy, Claire, St. James's Hospital, Dublin, Ireland
  • Jayawardene, Satish, St. James's Hospital, Dublin, Ireland
  • Griffin, Brenda, St. James's Hospital, Dublin, Ireland
  • Sexton, Donal J., St. James's Hospital, Dublin, Ireland
Background

Young adulthood represents a vulnerable period for patients living with Chronic Kidney Disease (CKD). Electronic communication is a preferred method of accessing health information among many young adults. The 2024 KDIGO CKD Guidelines identify transition from paediatric to adult care as a high-risk period, while UNICEF recognises young adulthood as a critical stage for health investment. Digital health interventions may support preventative CKD care and improve patient engagement.

Methods

Following research ethics committee approval, non-identifiable data were extracted for patients aged 16–26 years attending a tertiary nephrology service between January 2023-present day. Data were obtained from the electronic health record (EHR) and myPatientSpace, a cloud-based digital health platform with a smartphone application. The platform imports laboratory results from linked EHRs alongside patient and clinician-entered data. Variables collected included: age, sex, diagnosis, CKD aetiology, blood pressure (BP), urine protein quantification, creatinine, cystatin C, prescription of guideline-directed therapies (renin-angiotensin system inhibitors (RASi), sodium-glucose cotransporter-2 inhibitors (SGLT2i), and statins). Engagement was assessed through onboarding rates and login activity.

Results

121 young adults were identified, of whom 81 were onboarded to the platform. Disease aetiology differed from general adult nephrology cohorts, with predominant conditions including Congenital Anomalies of the Kidney and Urinary Tract (n=15, 12.4%), Sickle Cell Nephropathy (n=12, 9.9%), Glomerulonephritis (n=9, 7.4%), Tuberous Sclerosis Complex (n=7, 5.7%), and Cystic Kidney Disease (n=7, 5.7%). Five patients (4.1%) had undergone Stem Cell Transplantation. Blood Pressure (BP) recordings were available for 105 patients, with 53 (50%) achieving a BP <130/80mmHg, 31 (30%) < 120/80mmHg. Eight patients were prescribed SGLT2i therapy, 42 RASi therapy, with additional patients potentially eligible.

Conclusion

Digital health interventions may support preventative, guideline-directed CKD care in young adults. Our mHealth platform improved characterisation of this cohort, identified patients potentially eligible for disease-modifying therapies, and highlighted opportunities to improve BP control.
Future work will focus on remote monitoring, health literacy, and patient-reported outcome measures.

Acknowledgment

We would like to acknowledge the team at myPatientSpace for their contribution to this work. Dr McAnallen would like to acknowledge support from the Royal City of Dublin Hospital Trust.