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Kidney Week

Abstract: FR-PO1058

Patient-Reported Dialysis Recovery Time Before and After the Initiation of Hemodiafiltration

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Lasky, Rachel A., Renal Research Institute, New York, New York, United States
  • Ficociello, Linda, Renal Research Institute, New York, New York, United States
  • Hippen, Benjamin E., Fresenius Medical Care Global Medical Office, Waltham, Massachusetts, United States
  • Chatoth, Dinesh K., Fresenius Medical Care Global Medical Office, Waltham, Massachusetts, United States
Background

Hemodiafiltration (HDF) is increasingly being adopted as a dialysis modality in the US and has the potential to improve patient-centered outcomes. One important patient-reported outcome is dialysis recovery time, which reflects the time required to return to normal activities after a treatment session. Shorter recovery times may indicate improved treatment tolerability and better quality of life for patients receiving dialysis. This analysis evaluates changes in patient-reported recovery time among individuals who transitioned from in-center hemodialysis (ICHD) to HDF.

Methods

As part of routine clinical care, FKC patients are asked, “How long did it take for you to recover from your last dialysis session and resume your normal, usual activities?” every two weeks starting in July of 2025. Responses included “<2 hours”, “2-6 hours”, “7-12 hours”, “13-24 hours”, >24 hours”, “did not recover”, or “patient declined/unable to respond”. The current analysis included patients from a single dialysis clinic that transitioned from ICHD to HDF in late 2025/early 2026. We compared the earliest documented response for each patient and the latest response after having been treated with HDF with AutoSub plus (through March 2026).

Results

A total of 35 patients were included in the analysis. Prior to dialyzing with HDF, 68.9% of patients reported recovering from their previous dialysis session within 2 hours. This increased to 91.4% with the most recent responses, or a 33% increase overall. The average time between the latest response and starting HDF was 56 days.

Conclusion

These early findings suggest that HDF with AutoSub plus may improve patient-reported dialysis recovery time. Further studies will be needed to confirm these findings as HDF adoption expands in the U.S.

Funding

  • Commercial Support – Renal Research Institute