Abstract: TH-PO0888
Clinical and Echocardiographic Characteristics of Patients on Hemodialysis with Dialysis Vintage of More Than 30 Years: A Single-Center Comparison with Patients on Dialysis for 20 to 29 Years
Session Information
- Dialysis: Prescription, Physiology, and Treatment Optimization
October 22, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Funakoshi, Satoshi, Nagasaki Kidney Center, Nagasaki, Japan
- Ohno, Sakurako, Nagasaki Kidney Center, Nagasaki, Japan
- Sakai, Suzuna, Nagasaki Kidney Center, Nagasaki, Japan
- Imamura, Ryoichi, Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Background
The number of patients surviving on maintenance hemodialysis for decades has increased, but the clinical phenotype of patients with exceptionally long dialysis vintage remains poorly characterized. In particular, the factors distinguishing patients with dialysis vintage exceeding 30 years from those surviving 20–29 years are not well defined. We examined the clinical, social, laboratory, and echocardiographic characteristics of long-term hemodialysis survivors at a single center.
Methods
We retrospectively studied 40 maintenance hemodialysis patients with dialysis vintage of at least 20 years as of April 2024. Patients were divided into a 20–29-year group (n=26) and a ≥30-year group (n=14). We compared demographic characteristics, primary kidney disease, social background, laboratory data, and available echocardiographic parameters. Analyses were performed using available data for each variable because of missing values.
Results
Current age was similar between groups, whereas age at dialysis initiation was markedly younger in the ≥30-year group than in the 20–29-year group. Diabetes-related kidney disease was uncommon in this long-term survivor cohort overall. Conventional laboratory parameters, including hemoglobin, albumin, phosphorus, and intact parathyroid hormone, did not differ substantially between groups. Left ventricular ejection fraction was preserved and comparable in both groups. In contrast, selected echocardiographic structural parameters suggested a tendency toward greater long-term cardiac remodeling in the ≥30-year group, while indices of overt systolic dysfunction were not increased. Social background also appeared broadly similar between groups, although institutionalization was absent in the ≥30-year group.
Conclusion
Among hemodialysis patients who had already survived at least 20 years, those with dialysis vintage exceeding 30 years were distinguished primarily by younger age at dialysis initiation rather than by major differences in conventional laboratory or systolic echocardiographic parameters. These findings suggest that ultra-long-term hemodialysis survivors may represent a clinically homogeneous survivor cohort with preserved systolic function despite possible accumulation of structural cardiac changes.
Funding
- Private Foundation Support