Abstract: SA-PO0550
Prevalence and Clinical and Demographic Profile of Obstructive Sleep Apnea in Patients with Advanced Nondialysis-Dependent CKD at a Tertiary Care Hospital
Session Information
- CKD: Clinical - Therapies, CKM Health, Special Populations, and More
October 24, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2202 CKD (Non-Dialysis): Clinical, Outcomes, and Trials
Authors
- Lohia, Priyangani, IPGMER, Kolkata, West Bengal, India
- Pal, Atanu, IPGMER, Kolkata, West Bengal, India
- Maulik, Bibek, IPGMER, Kolkata, West Bengal, India
- Mahapatra, Rima, IPGMER, Kolkata, West Bengal, India
Background
Obstructive Sleep Apnea (OSA) is a common yet under- recognized comorbidity in patients with Chronic kidney disease (CKD), potentially worsening cardiovascular outcomes. This study aimed to determine the prevalence of OSA in patients with advanced CKD (Stages 3, 4 and 5) not yet requiring dialysis and correlate presence of OSA with demographic and clinical profile of the patient.
Methods
A cross-sectional observational study was conducted at the Department of Nephrology, IPGME&R and SSKM Hospital, West Bengal, India.
Adults aged 18–65 years with CKD Stage 3, 4 or 5 (GFR <60 ml/min/1.73m2), BMI <27.5 kg/m2, and hemoglobin >7 g/dL were enrolled.
Patients were screened for OSA using the Berlin Questionnaire and STOP BANG questionnaire. Those at high risk for OSA underwent polysomnography. Association was assessed between various clinical and laboratory parameters.
Results
311 patients were screened. Mean age was 43.41 ± 12.10 years, with 64% males.
92 patients (29.6%) were found to be at high risk for OSA and underwent polysomnography. Prevalence of OSA was 27.3% (85 patients). Out of 85 patients, 12 (14.1%) had severe OSA, 33 (38.8%) had moderate OSA and 40 patients (47.05%) had mild OSA.
OSA prevalence and severity increased with higher Berlin Questionnaire scores. Sleep fragmentation and pulmonary hypertension was significantly associated with more severe OSA (p 0.001).
Presence of OSA had positive correlation with hypertension, diabetes mellitus (p 0.001), Ischemic Heart disease (p 0.003) and duration of diabetes mellitus. Disease severity had a significant association with KDIGO GFR staging (p 0.005), residual renal function (p 0.001), Anthropometric parameters, glycemic control, hyperphosphatemia, but not with KDIGO Albuminuria categories (p 0.643).
Conclusion
OSA is widely prevalent in advanced CKD patients prior to dialysis. These findings align with previous studies showing increased OSA burden in CKD patients. The use of validated screening tools like the Berlin questionnaire and STOP- BANG questionnaire proved effective in identifying the patients at risk. Routine OSA screening using validated tools is recommended to facilitate early diagnosis and management. It can have a significant impact on cardiovascular health leading to better patient outcomes.
Acknowledgment
Thankful to all patients enrolled in the study and health care professionals associated with care of the patients involved in the study.
Funding
- Government Support – Non-U.S.