Kidney Week

Abstract: TH-PO1169

Mortality in Older Patients Undergoing CKRT

Session Information

• Geriatric Nephrology: Advancing Care for Older Adults
  October 22, 2026 | Location: Exhibit Hall A, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Geriatric Nephrology

• 1300 Geriatric Nephrology

Authors

• Paz Cortes, Jose Armando, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Jose Armando Paz Cortes, MD, MBBS

• Mercado Hernández, Yazmin Alejandra, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Yazmin Alejandra Mercado Hernández, MD

• Vega, Olynka, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Olynka Vega, MD, MS

• Rincon-Pedrero, Rodolfo, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Rodolfo Rincon-Pedrero, MD

• Correa-Rotter, Ricardo, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Ricardo Correa-Rotter, MD

• Fonseca-Correa, Jorge Ignacio, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Jorge Ignacio Fonseca-Correa, MD

Background

Advanced age is associated with poor outcomes in critically ill adults with AKI. This study aimed to characterize the clinical features and mortality of elderly patients undergoing CKRT in our center.

Methods

Between January 2016 and December 2025, 92 adults aged ≥60 years underwent CKRT at a tertiary referral center in Mexico City. Patients were stratified into six age groups: 60-64 (n=26), 65-69 (n=28), 70-74 (n=21), 75-79 (n=10), 80-84 (n=4), and ≥ 85 years (n=3). Predictors for in-hospital, 30-, 60-, and 90-day mortality and age effects were analyzed using multivariable Cox regression analysis.

Results

Mean age for the sample was 69±7 y/o, 38% were female, with a mean BMI of 26.5±5 kg/m2 and CCI of 6.3±2.7. During their ICU stay, 98% required vasopressors and 92% ventilatory support, SOFA score was 12±2.5. Among the 92 patients, 67 (72.8%) died in hospital (35% within the first week after CKRT start), 68 (73.9%) at 30 days, and 70 (76.2%) at 90 days. Median time to death after CKRT initiation was 5.5 days (IQR 2, 12.5, range 0-91 days). Volume overload was the reason for CKRT in 37.8% of cases. Sepsis was the cause of death in 48.9%. Postoperative AKI (aHR, 7.85; 95% CI, 2.18-28.22; p = 0.001), hypovolemic AKI (aHR, 21.69; 95% CI, 4.51-104.19; p = 0.0001), tumor lysis syndrome (aHR, 12.17; 95% CI, 1.51-97.82; p = 0.018), hepatobiliary disease (aHR, 7.83; 95% CI, 1.74-35.22; p = 0.007), maximal dose of norepinephrine (aHR, 1.65; 95% CI, 1.035-2.63; p = 0.0352) and SOFA Score (aHR, 1.108; 95% CI, 1.002-1.225; p = 0.0466) were associated with 30-day mortality. There was no difference in mortality between age groups.

Conclusion

In adults aged ≥ 60 years undergoing CKRT, in-hospital and early mortality was high. Age group was not associated with increased risk of mortality. The high mortality found in this cohort should be a reminder to take into account during shared decision-making when considering CKRT in critically ill elderly patients.