Abstract: SA-PO0308
AKI in Pregnant Adolescents in Pakistan
Session Information
- AKI: Epidemiology and Risk Factors
October 24, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 101 AKI: Epidemiology, Risk Factors, and Prevention
Author
- Maqsood, Zainab, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan
Background
Adolescent pregnancy remains a major public health concern in developing countries, particularly in Pakistan, where limited antenatal care and socioeconomic challenges contribute to increased maternal morbidity. Acute Kidney Injury (AKI) during pregnancy is a serious complication associated with significant maternal and fetal adverse outcomes. However, limited local data are available regarding the spectrum and outcomes of AKI among adolescent pregnant females.
Objective: To determine the spectrum, risk factors, and maternal-fetal outcomes of acute kidney injury in adolescent pregnancies presenting at a tertiary care hospital in Pakistan
Methods
This descriptive cross-sectional study was conducted in the Department of Obstetrics & Gynecology in collaboration with the Nephrology Unit at a tertiary care hospital in Pakistan over a period of one year. Adolescent pregnant females aged 13–19 years diagnosed with AKI according to KDIGO criteria were included. Data regarding demographic characteristics, gestational age, obstetric complications, laboratory parameters, causes of AKI, mode of delivery, maternal complications, and fetal outcomes were recorded. Patients with pre-existing chronic kidney disease or renal anomalies were excluded. Statistical analysis was performed using SPSS version 26.
Results
A total of 80 adolescent pregnant patients with AKI were included. The mean age was 17.6 ± 1.2 years. The most common causes of AKI were hypertensive disorders of pregnancy including preeclampsia/eclampsia (35%), sepsis (27.5%), postpartum hemorrhage (18.7%), and obstructed labor (11.3%). Oliguria was observed in 62% of patients, while 25% required hemodialysis. Maternal complications included ICU admission (30%), disseminated intravascular coagulation (12%), and maternal mortality (8%). Adverse fetal outcomes included preterm birth (38%), low birth weight (42%), stillbirth (15%), and neonatal intensive care admission (28%). Delayed presentation and lack of antenatal care were significantly associated with poor outcomes
Conclusion
Acute kidney injury in adolescent pregnancies is associated with substantial maternal and perinatal morbidity and mortality. Hypertensive disorders and sepsis were the leading etiological factors. Early identification of high-risk pregnancies, improved antenatal surveillance, timely referral, and multidisciplinary management may help reduce the burden of AKI and improve outcomes in adolescent mothers.