Abstract: TH-PO0709
Global Research Trends in Acute Kidney Injury and Continuous Renal Replacement Therapy in Critical Care: A Bibliometric Analysis, 2000-2025
Session Information
- AKI: Prevention, Diagnostics, and Management
October 22, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 101 AKI: Epidemiology, Risk Factors, and Prevention
Authors
- Asif, Aleena, University of Alabama at Birmingham Health System, Birmingham, Alabama, United States
- Tolwani, Ashita J., University of Alabama at Birmingham Health System, Birmingham, Alabama, United States
Background
Acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) represent a major focus of critical care research, yet no comprehensive bibliometric analysis has mapped the global evolution of this field. This study characterises the global AKI and CRRT research landscape from January 2000 through March 2025.
Methods
Web of Science Core Collection and Scopus were searched using standardized AKI- and CRRT-related search terms adapted for each database. After deduplication, 2,938 publications were analysed using the bibliometrix R package (v4.3.0) and VOSviewer. Analyses included publication trends, country and institutional productivity, keyword co-occurrence, thematic mapping, and CRRT terminology evolution.
Results
Annual output increased from 46 publications in 2000 to 314 indexed through March 2025, with sustained growth and notable surges coinciding with landmark RCTs and guideline publications.
Conclusion
AKI and CRRT research have grown exponentially over 25 years, driven by landmark RCTs and guideline publications. Research output is concentrated in high-income countries, highlighting a critical collaboration gap in low- and middle-income countries despite their disproportionate AKI burden. Emerging themes of machine learning, precision medicine, and novel extracorporeal therapies signal the next frontier of the field. These findings provide a data-driven roadmap for researchers, funders, and clinicians to priorities future AKI and CRRT investigation.