Abstract: SA-PO0287
Demographic, Causative, and Outcome Variations of AKI in Two Different Economic Settings
Session Information
- AKI: Epidemiology and Risk Factors
October 24, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 101 AKI: Epidemiology, Risk Factors, and Prevention
Authors
- Hewa Wellalage, Dharshi, Barts Health NHS Trust, London, England, United Kingdom
- Yadav, Satender Kumar, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, England, United Kingdom
- Stickland, Mary A., Barking Havering and Redbridge University Hospitals NHS Trust, Romford, England, United Kingdom
- Silva, Nalinda, Barts Health NHS Trust, London, England, United Kingdom
- Samad, Nasreen, Barts Health NHS Trust, London, England, United Kingdom
Background
AKI is a global health issue with significant mortality, morbidity and financial burden. Comparing the demographic, causative and outcome characteristics in different settings help effective planning and resource allocation.
Methods
Our study compared 75 in hospital patients from Sri Lanka (lower middle income) and the United Kingdom (higher income) over a period of 3 months. RIFLE criteria was used to detect AKI in Sri Lanka and KADIGO criteria was used in the UK. Community acquired and hospital acquired AKI were included.
Results
There was a male predominance which was more obvious in the Sri Lankan study (66%) versus 50.6% in the UK.
Sri Lankan patients were comparatively younger. 78% patients in the UK study were over 60 years whereas only 49 % Sri Lankan patients were over 60 years. 38 % of Sri Lankan patients were between 40 -60 years.
Diabetes and hypertension were common comorbidities in both settings. Cardiac disease was slightly commoner in the UK (34 %) compared with Sri Lanka (16%).
Infections were the commonest cause in both settings. Infections were responsible for 57% AKI in the UK and this was 44 % in Sri Lanka.
Prerenal causes (36 %) and obstruction (12 %) were the next common causes in the UK group.
Obstruction (14 %) and prerenal AKI (10 %) were among the next in the Sri Lankan group.
Length of the hospital stay was over 16 days in 53 % AKI patients in the UK. Only 14 % of Sri Lankan patients stayed this long. Most of the Sri Lankan patients were discharged between 6- 10 days (42%).
11 UK patients needed renal replacement therapy (RRT) and 6 of them remained dialysis dependent. 16 patients from Sri Lanka needed RRT and only 4 remained dialysis dependent.
There were 17 deaths among UK patients whereas only 5 deaths occurred among Sri Lankan patients.
Conclusion
The AKI patient population seems to be younger in the developing world. Main causative factor is infections in both settings. However type of the infection was not analysed.
Length of the hospital stay, long term dialysis dependency and the deaths were less in the Sri Lankan patients compared to UK. This reflects the aging population in the developed world. Sri Lankan group was younger with early recovery and less mortality.
One of the main limitations of this study is that Sri Lankan data was collected from December 2013 to March 2014 whereas the UK data was collected from January 2026 to April 2026.