Kidney Week

Abstract: TH-PO1274

ACTIVE-PD: Supervised Physical Exercise Improves Maximal Oxygen Consumption (VO2max) and Physical Function in Patients on Automated Peritoneal Dialysis

Session Information

• Late-Breaking Research Posters
  October 22, 2026 | Location: Exhibit Hall A, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 802 Dialysis: Home Dialysis and Peritoneal Dialysis

Authors

• Mariaca Ortiz, Yadira, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Yadira Mariaca Ortiz, MD

• Barrera-Hoffmann, Christopher, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Christopher Barrera-Hoffmann, MD

• Peña Delgado, Gabriela Michelle, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Gabriela Michelle Peña Delgado, MD

• Arrieta Damian, Andrea Lilian, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Andrea Lilian Arrieta Damian, MD

• Leal Escobar, Gabriela, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Gabriela Leal Escobar, MSc

• Ramirez-Calvillo, Luis Daniel, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Luis Daniel Ramirez-Calvillo, MD, MSc

• Cano Escobar, Karla Berenice, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico

Karla Berenice Cano Escobar, MD

Background

Physical inactivity affects up to 90% of patients receiving kidney replacement therapy, yet exercise interventions in peritoneal dialysis (PD) remain understudied. We evaluated the effect of a 12-week individualized supervised exercise program on functional and aerobic capacity in patients undergoing automated PD (APD).

Methods

We conducted a prospective, single-center, quasi-experimental before-and-after study in adults on APD. Participants completed individualized aerobic and resistance exercise 3–5 times/week at moderate intensity (Borg 5–7) for 35–50 minutes/session, with remote monitoring. Functional capacity was assessed before and after intervention using SPPB, 6-minute walk test (6MWT), 30-second sit-to-stand (STS30), handgrip dynamometry, and estimated peak VO2 and METs derived from cycle-ergometer stress echocardiography.

Results

Twenty-five patients were included; 18 (72%) completed ≥80% of the prescribed program. In intention-to-treat analysis, SPPB improved from 10.28±1.43 to 10.88±1.33 (p=0.029), handgrip strength from 20.95 [16.30–25.65] to 23.55 [19.53–28.57] kg (p=0.031), and STS30 from 10.0 [9.0–11.0] to 13.5 [12.0–15.25] repetitions (p<0.001). Estimated peak VO2 increased from 19.59±6.29 to 22.28±7.60 mL/kg/min and METs from 5.60±1.80 to 6.37±2.17 (both p=0.011). Among completers, peak VO2 increased by 4.50 mL/kg/min and METs by 1.29 (both p<0.001). Change in METs was greater in completers than non-completers (+1.29±1.16 vs −0.56±1.05; p=0.002), with parallel improvements in 6MWT, strength, STS30, and fat-free mass. No relevant exercise intolerance events occurred.

Conclusion

A 12-week individualized supervised exercise program was associated with clinically meaningful improvements in aerobic capacity, physical performance, and muscle strength in patients on APD.

Figure 2. (A) Estimated peak VO2; (B) functional capacity in METs;
(C) peak power achieved; and (D) exercise duration.