Abstract: TH-PO1294
Can Inferior Vena Cava Diameter and Collapsibility Index Predict Renal Response to Diuretic Therapy in Heart Failure?
Session Information
- Late-Breaking Research Posters
October 22, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Cardiovascular-Kidney-Metabolic Health
- 602 Cardiovascular-Kidney-Metabolic Health: Clinical
Authors
- Avci, Muammer, TC Saglik Bakanligi Isparta Sehir Hastanesi, Isparta, Isparta Province, Turkey
- Kutlu, Özgür Timuçin, TC Saglik Bakanligi Isparta Sehir Hastanesi, Isparta, Isparta Province, Turkey
Background
Renal venous congestion is one of the most important factors causing a reduction in estimated glomerular filtration rate (eGFR) in patients with cardiorenal syndrome. An increase in creatinine may lead to the discontinuation of diuretics required for decongestive treatment, thereby increasing mortality and morbidity. We aimed to investigate the relationship between inferior vena cava (IVC) diameter and collapsibility index and the renal response to diuretic therapy.
Methods
A total of 125 hypervolemic patients presenting with decompensated heart failure were included in the study. Patients with an absolute indication for dialysis were excluded. At presentation, the maximum and minimum IVC diameters were measured, and the collapsibility index was calculated. Intravenous furosemide was then initiated. Creatinine levels measured at presentation and on the day after furosemide initiation were entered into IBM SPSS Statistics and analyzed.
Results
The IVC diameter at initial presentation was statistically significantly greater in patients whose creatinine decreased (n=62) than in those whose creatinine increased (n=63, p = 0.034). The IVC collapsibility index tended to be higher in patients whose creatinine decreased, although the difference did not reach statistical significance (p = 0.187).The area under the curve for IVC diameter was 0.610.The optimal cutoff value for IVC diameter was 21.56 mm, with a sensitivity of 56.5% and a specificity of 66.7%. The ability of IVC diameter to predict a decrease in creatinine was weak to moderate. A subgroup analysis was performed by selecting patients with systolic blood pressure ≥100 mmHg and C-reactive protein ≤50 mg/L. IVC diameter tended to be greater in patients whose creatinine decreased, but the difference was not statistically significant (p = 0.085). In this subgroup, the IVC collapsibility index also tended to be higher in patients whose creatinine decreased, although the difference was not statistically significant (p = 0.774).
Conclusion
An IVC diameter greater than 21.56 mm supports the likelihood that creatinine may decrease after diuretic treatment. An inverse correlation was observed between the IVC collapsibility index and the decrease in creatinine, but this correlation was not statistically significant. . As the study continues, the inclusion of more patients may yield more precise and robust results.