Basic/Clinical Science Session
The Aldosterone Spectrum: Bridging Physiology, Pathophysiology, and Clinical Practice
October 24, 2026 | 02:00 PM - 04:00 PM
Location: Room 205, Convention Center
Session Description
Dysregulated, or renin-independent, aldosterone production significantly contributes to hypertension, cardiovascular disease, and CKD. This session explores the mechanisms and pathophysiology of primary aldosteronism, with an emphasis on its effects on kidney health. Best practices for screening, diagnosing, and evaluating aldosteronism, including adrenal venous sampling, are discussed. Additionally, the roles of mineralocorticoid receptor antagonists, aldosterone synthase inhibitors, and emerging siRNA therapies are reviewed.
Learning Objective(s)
- Define the role of aldosterone in maintaining potassium and volume homeostasis
- Describe the pathophysiology of renin-independent aldosteronism and how it affects kidney and cardiovascular health
- Outline current best practices for screening, diagnosing, and subtyping primary aldosteronism, including the use and interpretation of adrenal venous sampling
- Evaluate the efficacy and mechanisms of and indications for mineralocorticoid receptor antagonists, aldosterone synthase inhibitors, and emerging siRNA therapies
Learning Pathway(s)
- Cardiovascular-Kidney-Metabolic (CKM) Health
- CKD Non-Dialysis
Moderators
Presentations
- Essential Role of Aldosterone in Sodium, Potassium, and Volume Homeostasis
02:00 PM - 02:30 PM
- Dangers of Dysregulated Aldosteronism on Kidney and Cardiovascular Health
02:30 PM - 03:00 PM
- Uncovering Primary Aldosteronism with Effective Screening and Diagnosis
03:00 PM - 03:30 PM
- Novel Aldosterone-Focused Therapies for Hypertension and Kidney Health
03:30 PM - 04:00 PM