Basic/Clinical Science Session
Advancing Pluripotent Stem Cell-Generated Human Kidney Models
October 22, 2026 | 02:00 PM - 04:00 PM
Location: Mile High Ballroom 4D, Convention Center
Session Description
Kidney functions reflect the interplay among diverse cell types, posing challenges for in vitro modeling and tissue replacement. Cell diversity reflects the kidneys' multilineage origin and lineage-specific developmental programs driven by cell interactions within and across lineages. Experts address, assess, and critique advanced stem cell-generated, human kidney models that embrace lineage diversity to generate complex functional systems. Advancing human kidney models can improve insights into human physiology, disease modeling, drug discovery, and kidney replacement.
Learning Objective(s)
- Distinguish between organoids and assembloids
- Explain the potential clinical benefit of advanced human kidney models in addition to kidney replacement
- Outline the next goals in advancing stem cell-generated human kidney models toward the clinic
Learning Pathway(s)
- Genetic Diseases and Development
- Kidney Biology and Physiology
Moderators
Presentations
- Development-Directed Assembly of Human Kidney Models
02:00 PM - 02:30 PM
- Modeling Function and Disease with Multi-Progenitor-Derived Human Kidney Assembloids
02:30 PM - 03:00 PM
- Interconnection of Epithelial Networks in Multi-Progenitor-Derived Human Kidney Models
03:00 PM - 03:30 PM
- Macrophage-Kidney Assembloid: Modeling Microenvironment Contributions to Kidney Pathophysiology
03:30 PM - 04:00 PM