Clinical Practice Session
Complement in Glomerular Diseases in the Era of New Anticomplement Drugs
October 24, 2026 | 10:30 AM - 12:30 PM
Location: Four Seasons Ballroom 4, Convention Center
Session Description
Complement plays a central role in most glomerular diseases. Complement activation leads to glomerular accumulation of complement proteins and subsequent inflammation. New anticomplement drugs are now available to treat glomerular diseases associated with complement activation. This session addresses four disease entities: IgAN, membranous nephropathy, thrombotic microangiopathy (TMA), and C3 glomerulopathy (C3G), all of which show significant complement activation. The session provides an overview of the complement pathways in these diseases, followed by the role of new anticomplement drugs in their treatment.
Learning Objective(s)
- Evaluate complement pathways using kidney biopsy, including newer methodologies
- Identify the complement pathways in IgAN and evaluate the role of anticomplement drugs
- List the complement pathways in membranous nephropathy and evaluate the role of anticomplement drugs
- Identify the complement pathways in C3G and TMA, and evaluate the role of anticomplement drugs in both diseases
Learning Pathway(s)
- Glomerular Diseases
- Pathology
Moderators
Presentations
- How Can Kidney Biopsy Help in Evaluation of Complement in the Era of Anticomplement Drugs?
10:30 AM - 11:00 AM
- Complement in IgAN in the Era of Anticomplement Drugs
11:00 AM - 11:30 AM
- Complement in Membranous Nephropathy in the Era of Anticomplement Drugs
11:30 AM - 12:00 PM
- Complement in C3 Glomerulopathy and Thrombotic Microangiopathy in the Era of Anticomplement Drugs
12:00 PM - 12:30 PM