ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Teaching Machines Kidney Biology: Foundation Models That Learn Once and Generalize Everywhere

October 22, 2026 | 02:00 PM - 04:00 PM

Location: Room 603, Convention Center

Session Description

Artificial intelligence (AI) is increasingly used in medicine, but most tools are built for one single, narrow task at a time. Foundation models are different. They first learn the basic "language" of a system and can then apply it to many problems. In kidney research, a foundation model can learn core kidney biology by integrating genetics, single-cell and spatial data, pathology images, and clinical information. This session explains what foundation models and GPT-style AI are and why they may become a critical decision layer in kidney research, trials, and care.

Learning Objective(s)

  • Describe what foundation models and GPT-style AI are, and explain how they differ from traditional single-purpose analytic tools used in medicine
  • Explain how integrating genetics, single-cell and spatial biology, pathology images, and clinical data enables AI models to learn core kidney biology
  • Identify practical applications of kidney foundation models for patient stratification, clinical trial design, and therapeutic target evaluation
  • Describe current limitations, risks, and validation challenges associated with applying AI in kidney research and clinical care

Learning Pathway(s)

  • Other
  • Pathology

Moderators

Presentations