Posters
CKM Axis: Vascular Dysfunction, Atherosclerosis, and Heart Failure in Kidney Diseases
October 22, 2026 | 10:00 AM - 12:00 PM
Location: Exhibit Hall A, Convention Center
Session Description
Poster Session
Posters
The STRIKE Platform Enables Cross-Species siRNA Delivery and Gene Silencing in the Kidney Proximal Tubules
Valency Mediates Targeted siRNA Delivery and Knockdown Efficiency Along the Kidney Proximal Tubule Axis
Endothelial-Fibroblast Organoids as a Mechanistic Model of Cardiovascular-Kidney-Metabolic Disease
A Novel Adult Three-Dimensional (3D) Human Cardiac Organoid Model of Cardiac Fibrosis in CKD
Analysis of Autonomic Dysfunction in a Late-Stage CKD Model via Custom Large-Scale Rat Heart Rate Variability Analysis
Distinct Molecular Signature of Renal Afferent Neurons
Increased RNA Content Identifies a Molecularly Specialized Subset of Renal Afferent Neurons
Tubular Cells Promote a Selective Shift Toward Tonic Firing in Renal Afferent Neurons (RANs)
Loss of Bradykinin B1-B2 Signaling Disrupts Renal Afferent Feedback and Drives Sympathoexcitation
High Phosphate-Induced Hypertension Is Mediated by Central Nervous System (CNS) Translocation of Fibroblast Growth Factor 23 and Occurs via Fibroblast Growth Factor Receptor 4 (FGFR4)-Dependent, Clathrin-Mediated Endocytosis with Partial Klotho Independence
Renal Macrophage Acetylcholine Signaling Regulates Salt-Sensitive Hypertension Through Modulation of NKCC2 Expression
Proteins Involved in Mitochondrial Metabolism, Immune Response, and Inflammation Are Decreased in Npffr2-Deficient Mice Fed a Low-Salt Diet
Activation of BK Channels Ameliorates Renal Fibrosis in an Angiotensin II (Ang II)-Induced Hypertensive Mouse Model
Multi-Omics Profiling Reveals Early Metabolic and Redox Kidney Stress Preceding Organ Damage in an LssV643L Hypertensive Salt-Sensitive Mouse Model
Dissecting Novel Pathways Associated with Hypertension and Related Kidney Damage
Evaluating Renal Vascular Morphology in High-Salt and High-Sucrose Dietary Rat Models
Circadian Clock Provides Beneficial Effects Against Endothelial Dysfunction by Regulating Mitochondrial Heme Biosynthesis
MTAP Dysregulation in Vascular Calcification: Mechanistic Insights and Translational Strategies
Spatial Activation of AGPS Drives CKD-Associated Vascular Calcification via Ether Lipid-Dependent Ferroptosis
DNMT3A Links Methionine Dysmetabolism to Vascular Calcification in CKD
Enhanced Atherosclerotic Plaque Inflammation After Murine Pyelonephritis Parallels Human Complex Plaques and Proposes CCL8 as a Proatherogenic Mediator
Damage-Associated Molecular Patterns Exacerbate Atherosclerotic Disease in CKD: Therapeutic Suppression by the Toll-Like Receptor Inhibitor Soluble TLR2
Loss of Indoleamine 2,3-Dioxygenase 1 Activity Protects Against Peripheral Artery Disease in a Murine Model of Cardiovascular-Kidney-Metabolic (CKM) Syndrome
Uremic Toxins Disrupt Skeletal Muscle Proteostasis Through Immunoproteasome Perturbation in Cardiovascular-Kidney-Metabolic (CKM) Syndrome
Circulating Osteopontin Mediates Cardiac Dysfunction After AKI
Renal Tubule-Specific Ablation of Natriuretic Peptide Receptor-A Signaling Activates Proinflammatory Mediators
Carnitine Acetyltransferase Attenuates CKD-Related Cardiomyopathy via STAT3-Regulated Mitochondrial Dysfunction and Cardiomyocyte Hypertrophy
α-Ketoglutarate Modulates Lipid Metabolism to Ameliorate Kidney Injury in Mice with Chronic Heart Failure
Free Fatty Acids Induce Fibroblast Growth Factor 23 Expression in the Heart and Thereby Promote Cardiac Hypertrophy in Nephrotic Syndrome
Role of miR-452-5p/TIMP-2/MMP-2 Pathway in the Pathophysiology of Cardiac Remodeling in Cardiovascular-Kidney-Metabolic Syndrome: A New Target
Goreisan Attenuates Cardiac Remodeling in CKD with Pressure Overload-Induced Cardiac Hypertrophy via Suppression of Aquaporin-1 Signaling
Podocyte DNA Damage Drives Myeloid Skewing Through Epigenetic Reprogramming of Hematopoietic Stem Cells, Promoting Cardiorenal Dysfunction
Cachexia Accelerates CKD-Induced Cardiomyopathy Through Maladaptive Muscle-Kidney Crosstalk
Effects of Long-Term SGLT2 Inhibition on Renin Cell Activation and Afferent Arteriolar Hypertrophy During Chronic Renin-Angiotensin System Suppression
Comparison of the Renal Effects of the GLP-1 Receptor Agonists Semaglutide and Retatrutide in Adolescent Male Mice
Fiber-Based Diets and Region-Specific Intestinal Expression of GLP-1 Receptor in a Rat Model of CKD