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Kidney Week

Abstract: TH-PO145

Effect of Obesity on Transplant Outcome One Year Post Kidney Transplant

Session Information

Category: Transplantation

  • 1802 Transplantation: Clinical

Authors

  • Alnimri, Muna, University of California Davis, Sacramento, California, United States
  • Friedman, Golnaz G., University of California, Davis Health, Sacramento, California, United States
Background

Kidney transplant is the preferred option of treatment for patients with Chronic kidney disease,studies have shown poor outcome for obese patients BMI≥30kg/m2 and more perioperative complications,the aim of this study is to compare outcomes of obese patients BMI ≥30kg/m2 to patients with BMI<30kg/m2.

Methods

A retrospective single center cohort study of adult kidney transplant recipients between 1/2014 - 1/2016 compairing 308 patient BMI<30 to110 patients BMI≥30,one year patient and graft survival, incidence of delayed graft function, average hospital stay,wound and cardiac complications, new onset diabetes after transplant (NODAT),proteinuria and rejection .

Results

Table1 shows obese patient with BMI≥30kg/m2 were older,diabetics,on peritoneal dialysis, had higher incidence of delayed graft function worse patient suvival in one year,other complcations were not significantly different among both groups

Conclusion

Kidney transplant recipients with BMI ≥30kg/m2 have higher incidence of mortality,delayed graft function than patients with BMI <30kg/m2.
Dietery counseling and referral for bariatric surgery is recommended for weight loss to improve post transplant outcome.

 BMI <30kg/m2BMI≥ 30kg/m2P value
Number of patients308110 
SEX  0.24
Females125(40.5%)44(40%) 
Males183(59.5%)66(60%) 
Mean age SD5053.70.02
Dialysis Modality  0.12
HD237(77%)79(72%) 
Peritoneal dialysis52(17%)26(23.9%) 
Predialysis20(7%)4(3.7%) 
living donor57(18%)8(7.3%)0.02
Deceased donor251(81.9%)102(92.7) 
DM94(30.5%)48(43.6%)0.01
Death 1 year2(0.65%)4(3.6%)0.024
Graft failure6(1.9%)3(2.7%)0.63
creatinine mean 1year1.4mg/dl1.6mg/dl0.22
Delayed graft function55(17.9%)38(35%)<0.001
NODAT19(6.2%)8(7.3%)0.69
Days in hospital >5Days122(39.6%)41(37.6%)0.67
Drain29(7%)30(27.3%)<0.001
Wound Infection3(1%)0(0%)0.3
Post transplant proteinuria>0.5gm/d55(17.9%)24(22%)0.174
Rejection 1Year post transplant10(3.2%)4(3.6%)0.58
Ischemic cardiac events8(1.9%)0(0%)0.09
Arrhythmias11(3.6%)5(4.6%)0.65