Abstract: TH-PO145
Effect of Obesity on Transplant Outcome One Year Post Kidney Transplant
Session Information
- Transplantation: Cardiovascular and Metabolic Diseases
October 25, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 1802 Transplantation: Clinical
Authors
- Alnimri, Muna, University of California Davis, Sacramento, California, United States
- Friedman, Golnaz G., University of California, Davis Health, Sacramento, California, United States
Background
Kidney transplant is the preferred option of treatment for patients with Chronic kidney disease,studies have shown poor outcome for obese patients BMI≥30kg/m2 and more perioperative complications,the aim of this study is to compare outcomes of obese patients BMI ≥30kg/m2 to patients with BMI<30kg/m2.
Methods
A retrospective single center cohort study of adult kidney transplant recipients between 1/2014 - 1/2016 compairing 308 patient BMI<30 to110 patients BMI≥30,one year patient and graft survival, incidence of delayed graft function, average hospital stay,wound and cardiac complications, new onset diabetes after transplant (NODAT),proteinuria and rejection .
Results
Table1 shows obese patient with BMI≥30kg/m2 were older,diabetics,on peritoneal dialysis, had higher incidence of delayed graft function worse patient suvival in one year,other complcations were not significantly different among both groups
Conclusion
Kidney transplant recipients with BMI ≥30kg/m2 have higher incidence of mortality,delayed graft function than patients with BMI <30kg/m2.
Dietery counseling and referral for bariatric surgery is recommended for weight loss to improve post transplant outcome.
BMI <30kg/m2 | BMI≥ 30kg/m2 | P value | |
Number of patients | 308 | 110 | |
SEX | 0.24 | ||
Females | 125(40.5%) | 44(40%) | |
Males | 183(59.5%) | 66(60%) | |
Mean age SD | 50 | 53.7 | 0.02 |
Dialysis Modality | 0.12 | ||
HD | 237(77%) | 79(72%) | |
Peritoneal dialysis | 52(17%) | 26(23.9%) | |
Predialysis | 20(7%) | 4(3.7%) | |
living donor | 57(18%) | 8(7.3%) | 0.02 |
Deceased donor | 251(81.9%) | 102(92.7) | |
DM | 94(30.5%) | 48(43.6%) | 0.01 |
Death 1 year | 2(0.65%) | 4(3.6%) | 0.024 |
Graft failure | 6(1.9%) | 3(2.7%) | 0.63 |
creatinine mean 1year | 1.4mg/dl | 1.6mg/dl | 0.22 |
Delayed graft function | 55(17.9%) | 38(35%) | <0.001 |
NODAT | 19(6.2%) | 8(7.3%) | 0.69 |
Days in hospital >5Days | 122(39.6%) | 41(37.6%) | 0.67 |
Drain | 29(7%) | 30(27.3%) | <0.001 |
Wound Infection | 3(1%) | 0(0%) | 0.3 |
Post transplant proteinuria>0.5gm/d | 55(17.9%) | 24(22%) | 0.174 |
Rejection 1Year post transplant | 10(3.2%) | 4(3.6%) | 0.58 |
Ischemic cardiac events | 8(1.9%) | 0(0%) | 0.09 |
Arrhythmias | 11(3.6%) | 5(4.6%) | 0.65 |