Abstract: SA-PO499
Description and Variability of Dietary Intake of Patients with Autosomal Dominant Polycystic Kidney Disease
Session Information
- ADPKD: Clinical Studies
October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Genetic Diseases of the Kidney
- 1001 Genetic Diseases of the Kidney: Cystic
Authors
- Betz, Melanie, University of Chicago Medicine, Chicago, Illinois, United States
- Chapman, Arlene B., University of Chicago, Chicago, Illinois, United States
Background
Nutrition counseling is imperative for Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients; proper intake of protein and sodium can delay cyst growth and reducing diet acid load may delay progression of disease.Little has been published describing the diet of ADPKD patients.Food records collected over 3 days are standard practice to account for daily variations in intake.However, it is unknown how much nutrient intakes vary and if three days of food records are necessary. The objective of this project was to describe the diet of ADPKD patients and to understand how much nutrient intake varies daily.
Methods
Three-day food records were collected in a genetic disorder nephrology clinic at University of Chicago Medicine. A Registered Dietitian provided food record instructions and analyzed the record with National Data Research System, 2017.Potential Renal Acid Load (PRAL) and the variability of nutrient intake between three days of food record for a single patient were calculated.
Results
A total of 22 patients were included in analysis with a mean age of 48.18years, BMI of 26.6kg/m2 and GFR of 58.29ml/min (n=15); 91% were Caucasian. See table for dietary analysis results and day-to-day variability.
Conclusion
ADPKD patients are consuming excess protein, sodium, saturated fat and cholesterol; whereas potassium, calcium and fiber intake is inadequate.These results showcase the importance of nutrition counseling for ADPKD patients.Nutrient intake varies greatly from day to day, highlighting the importance of capturing more than a single day when assessing diet.
Average Nutrient Intake and Daily Variability
| Average Intake | Variability | |
| Calories | 1929 | 29% |
| Protein | 81g | 42% |
| Fat | 85g | 41% |
| Carbohydrate | 209g | 37% |
| Sodium | 2770mg | 42% |
| Potassium | 2663mg | 35% |
| Phosphorus | 1257mg | 38% |
| Magnesium | 332mg | 33% |
| Calcium | 930mg | 47% |
| Cholesterol | 334mg | 56% |
| Fiber | 22g | 36% |
| % Calories from Saturated Fat | 13% | 42% |
| % Calories from Added Sugar | 2% | 63% |
| Potential Renal Acid Load (PRAL) | 9.09 mEq/day | 126% |