Abstract: PO0723
COVID-19 Infection in Patients with ESRD Requiring Hemodialysis
Session Information
- COVID-19: Dialysis Patients
October 22, 2020 | Location: On-Demand
Abstract Time: 10:00 AM - 12:00 PM
Category: Coronavirus (COVID-19)
- 000 Coronavirus (COVID-19)
Authors
- Anisimova, Anna, St. George's University School of Medicine, True Blue, Grenada
- Ripa, Valeria, Saint Barnabas Medical Center, Livingston, New Jersey, United States
- Almaz, Biruk, Saint Barnabas Medical Center, Livingston, New Jersey, United States
- Mistry, Nirav, Saint Barnabas Medical Center, Livingston, New Jersey, United States
- Rezai, Fariborz, Saint Barnabas Medical Center, Livingston, New Jersey, United States
Background
This case series assesses characteristics and outcomes of patients with confirmed novel coronavirus (SARS-CoV-2, COVID-19) infection and end stage renal disease (ESRD) requiring hemodialysis during the COVID-19 pandemic.
Methods
This is a single center retrospective study of 24 ESRD patients on hemodialysis who were admitted to Saint Barnabas Medical Center, a 597-bed acute care hospital in Livingston, New Jersey, and with a confirmed COVID-19 diagnosis between February 1st to April 5th, 2020. The characteristics, clinical course, and outcome were assessed and compared. In addition, a subgroup analysis was made between patients who expired (n=8) versus those who lived (n=16).
Results
The overall mortality rate was 33.3% vs. 21% in the general population with COVID-19. Among the 4 (16%) patients who required ICU admission and prolonged pressor support and invasive mechanical ventilation, 2 (50%) patients were successfully extubated and discharged from the hospital while the other 2 (50%) patients died. There were no statistical differences in laboratory values between patients who survived versus patients who died except C-reactive protein (CRP), p=0.002.
Conclusion
We report a mortality rate of 33.3% in our case series of 24 patients with ESRD on dialysis with concurrent COVID-19 infection. There was a statistical difference in CRP value between patients who died versus survived. Fifty percent of intubated patients were successfully extubated and discharged.