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Abstract: PO0723

COVID-19 Infection in Patients with ESRD Requiring Hemodialysis

Session Information

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Anisimova, Anna, St. George's University School of Medicine, True Blue, Grenada
  • Ripa, Valeria, Saint Barnabas Medical Center, Livingston, New Jersey, United States
  • Almaz, Biruk, Saint Barnabas Medical Center, Livingston, New Jersey, United States
  • Mistry, Nirav, Saint Barnabas Medical Center, Livingston, New Jersey, United States
  • Rezai, Fariborz, Saint Barnabas Medical Center, Livingston, New Jersey, United States
Background

This case series assesses characteristics and outcomes of patients with confirmed novel coronavirus (SARS-CoV-2, COVID-19) infection and end stage renal disease (ESRD) requiring hemodialysis during the COVID-19 pandemic.

Methods

This is a single center retrospective study of 24 ESRD patients on hemodialysis who were admitted to Saint Barnabas Medical Center, a 597-bed acute care hospital in Livingston, New Jersey, and with a confirmed COVID-19 diagnosis between February 1st to April 5th, 2020. The characteristics, clinical course, and outcome were assessed and compared. In addition, a subgroup analysis was made between patients who expired (n=8) versus those who lived (n=16).

Results

The overall mortality rate was 33.3% vs. 21% in the general population with COVID-19. Among the 4 (16%) patients who required ICU admission and prolonged pressor support and invasive mechanical ventilation, 2 (50%) patients were successfully extubated and discharged from the hospital while the other 2 (50%) patients died. There were no statistical differences in laboratory values between patients who survived versus patients who died except C-reactive protein (CRP), p=0.002.

Conclusion

We report a mortality rate of 33.3% in our case series of 24 patients with ESRD on dialysis with concurrent COVID-19 infection. There was a statistical difference in CRP value between patients who died versus survived. Fifty percent of intubated patients were successfully extubated and discharged.