ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on Twitter

Kidney Week

Abstract: PO2474

Renal Transplant Recipients Suffer Significantly More Complications After Breast Cancer Surgery but Benefit from Treatment at Transplant Centers

Session Information

Category: Transplantation

  • 1902 Transplantation: Clinical

Authors

  • Choubey, Ankur P., The University of Toledo Medical Center, Toledo, Ohio, United States
  • Parsikia, Afshin, Westchester Medical Center, Valhalla, New York, United States
  • Castaldi, Maria, Westchester Medical Center, Valhalla, New York, United States
  • Latifi, Rifat, Westchester Medical Center, Valhalla, New York, United States
  • Ortiz, Jorge, The University of Toledo Medical Center, Toledo, Ohio, United States
Background

Breast Carcinoma has the highest incidence of any cancer in adult females. The impact of kidney transplant (KT) on breast cancer surgery has not been examined. Our objective was to evaluate the influence of a previous KT on the short-term outcomes of mastectomy or lumpectomy.

Methods

A retrospective analysis was conducted using Nationwide Inpatient Sample (NIS) data between 2005 and 2014. Population included adult females with kidney transplant surgically treated for breast malignancy. Weighted multivariate regression models were employed to compare outcomes at transplant and non-transplant centers.

Results

398 women met the inclusion criteria. There was a greater proportion of African-American (p<0.001), and Hispanic women (p=0.01) compared to the cohort. KT recipients had more comorbidities and higher Elixhauser Comorbidity Index scores (p<0.001). We noted longer length of stay (p<0.001), higher expenditure (p=0.001), and complications (p<0.001). Specifically, rates of hematomas (p=0.041), acute renal failure (p<0.001), blood transfusion (p<0.001), fresh frozen plasma transfusion (p<0.001), cardiovascular (p<001), and other complications (p=0.012) were increased. There was no mortality among transplant recipients.
Weighted multivariate analyses highlight that rates of complication (p=0.040), and length of stay (p<0.001) are lower at transplant centers.

Conclusion

History of kidney transplant has a significant impact on the outcomes of mastectomy or lumpectomy. These patients suffer more post-operative adverse events. However, KT recipients experience superior outcomes at transplant centers.

Table 1. Patient Demographics, Outcomes, and Adjusted Outcomes for Kidney Transplant Recipients Treated at Transplant Centers.