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Kidney Week

Abstract: PO2459

Infection Rate at 1 Year of Deceased Donor Kidney Transplant in the Elderly

Session Information

Category: Transplantation

  • 1902 Transplantation: Clinical

Authors

  • Yousman, Wina, The University of Arizona, Tucson, Arizona, United States
  • Low, Nicole, The University of Arizona, Tucson, Arizona, United States
  • Wong, Wei Xiang, The University of Arizona, Tucson, Arizona, United States
  • Ariyamuthu, Venkatesh Kumar, The University of Arizona, Tucson, Arizona, United States
  • Tanriover, Bekir, The University of Arizona, Tucson, Arizona, United States
Background

There is limited publications about infection incidence rate in deceased donor kidney transplant (DDKT) recipients older than 65. The objective of this study is to examine our center specific infection incidence rate within one year of DDKT.

Methods

Retrospective chart review of DDKT (N=176) from July 2016 to December 2019 at Banner Medical Center in Tucson, AZ. Primary outcome was the infection incidence rate among recipients older than 65 year-old, including Cytomegalovirus (CMV) viremia and BK viremia (screened by monthly plasma PCR testing), or urinary tract infection (UTI) (diagnosed with positive urine culture and urinary symptoms within first year of transplant). We also fitted a multivariable logistic regression for the outcomes variables adjusted for demographics, KDPI, CIT, EPTS, and cPRA.

Results

The characteristics of the study cohort was shown in Table 1. Out of 176 patients, 63 patients (35.8%) were older than 65 year-old. There was no significant difference in the incidence rate of total infection, CMV viremia, BK viremia, and UTI in the elderly versus non-elderly patient (63.5% vs 51.3% p=0.11, 20.6% vs 11.5% p=0.10, 15.9% vs 11.5% p=0.41, 32.3% vs 28.3%, p=0.59). The multivariable logistic regression analysis (adjusted for ethnicity, KDPI, EPTS, cPRA, and CMV mismatch) did not show increased odds of all type of infections among older recipients.

Conclusion

The infection rate of elderly versus non-elderly who received DDKT were similar.

Table 1: Baseline Characteristics and Outcomes of Elderly vs. Non-eldery