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Abstract: PO0720

Clinical Symptoms in 44 Hemodialysis Patients Who Survived and Recovered from a Confirmed SARS-CoV-2 Infection and COVID-19 in Relation to Age and Hospitalization: An International Experience

Session Information

Category: Coronavirus (COVID-19)

  • No subcategory defined

Authors

  • Ruiz, Mauricio, DaVita Colombia, Bogota, Colombia
  • Brzosko, Szymon, DaVita Poland, Wroclaw, Poland
  • Serwanska-Swietek, Marta, DaVita Poland, Wroclaw, Poland
  • Kleophas, Werner, DaVita Germany, Dusseldorf, Germany
  • Krueger, Thilo, DaVita Germany, Dusseldorf, Germany
  • Frazao, Joao M., DaVita Portugal, Lisbon, Portugal
  • Silva, Fatima Ferreira, DaVita Portugal, Lisbon, Portugal
  • Al-Badr, Wisam H.A., DaVita Saudi Arabia, Riyadh, Saudi Arabia
  • Altaher, Atef Zohdi, DaVita Saudi Arabia, Riyadh, Saudi Arabia
  • Yahya, Rosnawati, DaVita Malaysia, Kuala Lumpur, Malaysia
  • Drozdz, Maciej, DaVita International, London, United Kingdom
  • Das, Partha, DaVita International, London, United Kingdom
  • Monteiro, Claudio Amorim, DaVita Kidney Care Brazil, Brasilia, Brazil
  • Jacobson, Stefan H., Karolinska Institutet, Stockholm, Stockholm, Sweden
Background

A novel coronavirus (SARS-CoV-2) is now rapidly spreading throughout the world. Patients undergoing long-term in-center hemodialysis (HD) are highly vulnerable given kidney failure, comorbidities, and the need for frequent visits to a dialysis facility.

Methods

A total of 610 patients on maintenance HD at DaVita clinics in 6 countries were tested for presence of infection with SARS-CoV-2 using polymerase chain reaction (PCR) between March 28 and May 18. Of these, 115 HD patients (19%) were positive. Information up to May 25, 2020, show that 44 patients have recovered. Clinical symptoms during infection with SARS-CoV-2 are reported from these 44 recovering survivors (Germany 13 patients, Poland 12, Portugal 12, Colombia 2, Saudi Arabia 3, and Malaysia 2) and classified into 4 categories: no symptoms, mild, moderate, or severe symptoms. Hospitalizations and time to recovery were also analyzed. Statistical comparisons were made using Chi-2 analysis and Kruskal-Wallis tests.

Results

Of the 44 patients recovering from COVID-19, 22 patients were ≥70 years and 9 patients were >80 years. Symptoms in relation to age, hospitalization, and time to recovery are shown below.

Conclusion

The majority of HD patients (66%) who recovered from COVID-19 had no or mild clinical symptoms during the infection. There were no significant differences in the occurrence of symptoms from SARS-CoV-2 in relation to age, hospitalization, or time to recovery. Additionally, old and frail HD patients with confirmed COVID-19 may have mild symptoms of the disease.

Percentage of HD Patients Who Recovered From Clinical Symptoms During Infection With SARS-CoV-2
 No symptomsMild symptomsModerate symptomsSevere symptoms
All patients27.338.631.82.3
< 70 years36.440.922.70
>= 70 years18.236.440.94.5
Hospitalized36.136.1252.8
Time to recovery (days)27253041