Abstract: PO0720
Clinical Symptoms in 44 Hemodialysis Patients Who Survived and Recovered from a Confirmed SARS-CoV-2 Infection and COVID-19 in Relation to Age and Hospitalization: An International Experience
Session Information
- COVID-19: Dialysis Patients
October 22, 2020 | Location: On-Demand
Abstract Time: 10:00 AM - 12:00 PM
Category: Coronavirus (COVID-19)
- 000 Coronavirus (COVID-19)
Authors
- Ruiz, Mauricio, DaVita Colombia, Bogota, Colombia
- Brzosko, Szymon, DaVita Poland, Wroclaw, Poland
- Serwanska-Swietek, Marta, DaVita Poland, Wroclaw, Poland
- Kleophas, Werner, DaVita Germany, Dusseldorf, Germany
- Krueger, Thilo, DaVita Germany, Dusseldorf, Germany
- Frazao, Joao M., DaVita Portugal, Lisbon, Portugal
- Silva, Fatima Ferreira, DaVita Portugal, Lisbon, Portugal
- Al-Badr, Wisam H.A., DaVita Saudi Arabia, Riyadh, Saudi Arabia
- Altaher, Atef Zohdi, DaVita Saudi Arabia, Riyadh, Saudi Arabia
- Yahya, Rosnawati, DaVita Malaysia, Kuala Lumpur, Malaysia
- Drozdz, Maciej, DaVita International, London, United Kingdom
- Das, Partha, DaVita International, London, United Kingdom
- Monteiro, Claudio Amorim, DaVita Kidney Care Brazil, Brasilia, Brazil
- Jacobson, Stefan H., Karolinska Institutet, Stockholm, Stockholm, Sweden
Background
A novel coronavirus (SARS-CoV-2) is now rapidly spreading throughout the world. Patients undergoing long-term in-center hemodialysis (HD) are highly vulnerable given kidney failure, comorbidities, and the need for frequent visits to a dialysis facility.
Methods
A total of 610 patients on maintenance HD at DaVita clinics in 6 countries were tested for presence of infection with SARS-CoV-2 using polymerase chain reaction (PCR) between March 28 and May 18. Of these, 115 HD patients (19%) were positive. Information up to May 25, 2020, show that 44 patients have recovered. Clinical symptoms during infection with SARS-CoV-2 are reported from these 44 recovering survivors (Germany 13 patients, Poland 12, Portugal 12, Colombia 2, Saudi Arabia 3, and Malaysia 2) and classified into 4 categories: no symptoms, mild, moderate, or severe symptoms. Hospitalizations and time to recovery were also analyzed. Statistical comparisons were made using Chi-2 analysis and Kruskal-Wallis tests.
Results
Of the 44 patients recovering from COVID-19, 22 patients were ≥70 years and 9 patients were >80 years. Symptoms in relation to age, hospitalization, and time to recovery are shown below.
Conclusion
The majority of HD patients (66%) who recovered from COVID-19 had no or mild clinical symptoms during the infection. There were no significant differences in the occurrence of symptoms from SARS-CoV-2 in relation to age, hospitalization, or time to recovery. Additionally, old and frail HD patients with confirmed COVID-19 may have mild symptoms of the disease.
Percentage of HD Patients Who Recovered From Clinical Symptoms During Infection With SARS-CoV-2
| No symptoms | Mild symptoms | Moderate symptoms | Severe symptoms | |
| All patients | 27.3 | 38.6 | 31.8 | 2.3 |
| < 70 years | 36.4 | 40.9 | 22.7 | 0 |
| >= 70 years | 18.2 | 36.4 | 40.9 | 4.5 |
| Hospitalized | 36.1 | 36.1 | 25 | 2.8 |
| Time to recovery (days) | 27 | 25 | 30 | 41 |