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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Abstract: PO0518

Impact of the Race Multiplier in the Estimated Glomerular Filtration Rate Equation on Care Delivery Among African-American CKD Patients

Session Information

Category: CKD (Non-Dialysis)

  • 2101 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention


  • Ahmed, Salman, Brigham and Women's Hospital, Boston, Massachusetts, United States
  • Mendu, Mallika L., Brigham and Women's Hospital, Boston, Massachusetts, United States

African-American patients with chronic kidney disease (CKD) have poorer outcomes, including in dialysis access placement and transplantation. Estimated glomerular filtration rate (eGFR) equations, which assign higher eGFR values to African-American patients, may be an inadvertent mechanism for inequitable outcomes. Electronic health record-based registries enable population-based examination of care across racial groups.


Cross-sectional study at two large academic medical centers and affiliated community primary care and specialty practices.


Of 2225 African-American patients, 743 (33.4%) would hypothetically be reclassified to a more severe CKD stage if the race multiplier were removed from the CKD-EPI equation. Similarly, 167 of 687 (24.3%) would be reclassified from stage 3B to stage 4. Finally, 64 of 2069 patients (3.1%) would be reassigned from eGFR > 20 ml/min/1.73m2 to eGFR < 20 ml/min/1.73m2, meeting the criterion for accumulating kidney transplant priority. Zero of 64 African-American patients with an eGFR <20 ml/min/1.73m2 after the race multiplier was removed were referred, evaluated or waitlisted for kidney transplant, compared to 19.2% of African-American patients with eGFR<20 ml/min/1.73m2 with default CKD-EPI equation.


Our study reveals a meaningful impact of race-adjusted eGFR on the care provided to the African-American CKD patient population.


  • Private Foundation Support