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Kidney Week

Abstract: PO0733

Outcomes of COVID-19 in ESRD Patients on Hemodialysis

Session Information

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Daifi, Chantale, Henry Ford Health System, Detroit, Michigan, United States
  • Uduman, Junior, Henry Ford Health System, Detroit, Michigan, United States
  • Yee, Jerry, Henry Ford Health System, Detroit, Michigan, United States
Background

The presentation, natural course, outcomes, and markers of COVID-19 among end stage renal disease (ESRD) have not been well defined. The objective of this study is to evaluate the outcomes of COVID-19 hospitalized and nonhospitalized outpatient ESRD patients. The secondary objectives are to evaluate mortality rate, hospital readmission rates, treatment methods, lengths of hospital stay, mechanical ventilation requirement, and acute respiratory distress syndrome (ARDS) between hospitalized and non-hospitalized patients.

Methods

This is a prospective, observational study evaluating the outcomes of hemodialysis patients who test positive for COVID-19 between March 10 to May 8, 2020 at a large regional health system in Southeast Michigan. Incenter hemodialysis patients, 18 years or older who tested positive for COVID-19 were included. Descriptive statistics are used, and continuous variables are presented as medians with interquartile ranges, and categorical variables are presented as percentages. Two-sided t-tests were used for exploratory analysis.

Results

97 of 192 patients tested positive for SARS-CoV-2. Hospitalization rate among COVID-19 positive patients were 76.3%. The most common presenting symptom was fever (63%). Overall mortality and readmission were 16.5% and 14.4%. Median length of hospital and intensive care unit stay was 7.6 and 8 days. Of the hospitalized patients, 17.6% required mechanical ventilation, and 53.9% developed ARDS, with a mortality of 85.7% in this group of patients. Leucopenia, C-reactive protein, peak ferritin and D-dimer corelated with mortality among hospitalized patients.

Conclusion

ESRD pose a higher risk for hospitalization, overall mortality was acceptable, although survival among patients requiring mechanical ventilation was low.