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Abstract: PO0808

Temporary Changes in Hemodialysis Parameters in Patients Affected by COVID-19 Infection: A Visual Guide

Session Information

Category: Dialysis

  • 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Navarrete, Jose E., Emory University, Atlanta, Georgia, United States
  • Franch, Harold A., Emory University, Atlanta, Georgia, United States
  • Lea, Janice P., Emory University, Atlanta, Georgia, United States
  • Cobb, Jason, Emory University, Atlanta, Georgia, United States
  • Rahbari-Oskoui, Frederic F., Emory University, Atlanta, Georgia, United States
  • Apata, Ibironke W., Emory University, Atlanta, Georgia, United States

Group or Team Name

  • Emory Renal COVID-19 Project
Background

ESKD patients on dialysis have been significantly affected by the COVID pandemic. By now, a substantial number of patients have survived the disease. We display graphically the temporary changes in dialysis parameters of patients that have survived COVID-19 infection.

Methods

All patients receiving hemodialysis at Emory dialysis centers diagnosed with COVID-19 infection between 3/1/20 to 1/31/21 who survived for at least 3 months were identified. The date of COVID-19 diagnosis was used to time-reference dialysis parameters including duration of hemodialysis, weight, ultrafiltration, mean arterial pressure pre-dialysis, hemoglobin, albumin, calcium, phosphorus, potassium, serum bicarbonate, absolute lymphocyte count and Kt/V. The temporary behavior of these parameters is presented graphically. Data manipulation, analysis and graphical display was performed using R-software and tidyverse package.

Results

96 patients were identified. 82% were African-American with a median age of 64y/o. 52% were male and 60% were diabetics, The median time on dialysis was 2.5 years. All studied parameters showed a significant deviation from baseline measurements obtained in the 60 days prior to the diagnosis of COVID-19. The parameter with the least amount of change was Kt/V. In the subsequent 2 months after diagnosis, all of the parameters studied returned to baseline except for Potassium, that remained below pre-morbid levels 2 months after the COVID-19 diagnosis. These changes are presented in Figure 1.

Conclusion

COVID-19 infection has a significant impact on hemodialysis parameters as presented in figure 1. The temporary variation of the most common parameters associated with COVID-19 infection presented in this study can be used as reference for patients, dieticians, and nephrologists caring for ESKD affected by COVID-19.