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Kidney Week

Abstract: PO0198

Risk Factors and Outcome Variables of Cardiorenal Syndrome Type 1 from the Nephrological Perspective

Session Information

Category: Acute Kidney Injury

  • 101 AKI: Epidemiology, Risk Factors, and Prevention


  • Patschan, Daniel, Medical School of Brandenburg, Brandenburg, Germany

In cardiorenal syndrome (CRS) type 1, acute cardiac failure or acute decompensation of chronic heart failure causes acute kidney injury (AKI). Every individual AKI episode increases the risk for chronic kidney disease (CKD) in the long-term. In this study we aimed to evaluate epidemiological characteristics and outcome variables of CRS type 1 individuals from the nephrology perspective.


The study was performed in a restrospective, observational manner. All AKI patients treated at the Brandenburg Hospital of the Medical School of Brandenburg between january and december 2019 were screened for diagnostic criteria of CRS type 1. Endpoints were in-hospital death, need for dialysis, and renal recovery.


During the screening, a total number of 1,189 subjects were diagnosed with acute kidney injury according to KDIGO. One-hundred ninety-eight (198 - 16.6%) out of these patients were assigned to the diagnosis CRS type 1. The overall in-hospital mortality was 19.2%. Non-survivors were not older than survivors. Nine point six (9.6) % of the patients required dialysis due to AKI, respective individuals were significantly older (84.6 +/-1.4 vs. 77.6 +/-0.7 years; p=0.002). Complete recovery of kidney function was observed in 86 individuals (43.4%), incomplete recovery occurred in 55 patients (27.8%), fifty-seven patients (28.8%) did not revover at all. Age-related differences were not identified. Sixty-four (32.2%) demission letters did not contain any cardiorenal diagnosis at all, nephrology follow-up recommendations were given in only 8%.


The incidence of CRS type 1 is high (∼16% of all in-hospital AKI subjects) and the mortality is higher than the average mortality of AKI in general. At the same time complete recovery of kidney function occurs less frequent. The kidney-related follow-up management of CRS type 1 needs to be significantly optimized in order to improve the long-term outcome of affected patients.