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Abstract: PO2245

Screening for Early CKD in School Children in Kano, Nigeria

Session Information

Category: CKD (Non-Dialysis)

  • 2101 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Authors

  • Mudi, Abdullahi, Bayero University College of Health Sciences, Kano, Nigeria
  • Abdu, Aliyu, Bayero University College of Health Sciences, Kano, Nigeria
  • Zent, Roy, Vanderbilt University Medical Center, Nashville, Tennessee, United States

Group or Team Name

  • VECD Fogarty Global Health Fellowship
Background

There has been an ongoing debate on the benefits of CKD screening in general especially as it relates to cost effectiveness and absolute relevance. However, screening for CKD in children will make a huge impact especially in low- and middle-income countries (LMIC) where treatment for End Stage CKD is not readily available due to high cost, shortage of skilled personnel and donor organs.
This NIH/VECD Fogarty Funded research aimed to determine the burden of early CKD among school children in Kano, Nigeria.

Methods

The study screened 228 school children (5-15 years) within Kano metropolis for CKD from February 2020 to February 2021. Information of participants’ socio-demographic profile and medical history was obtained through questioning. Participants’ height, weight and blood pressure were measured. They also had their spot urine assessed for albumin creatinine ratio (ACR), and blood for serum creatinine and estimated glomerular filtration rate (eGFR). Participants with abnormal findings had a a repeat assessment after three months for BP, ACR and eGFR

Results

The median age of the children was 13.0 (11.1-14.0) years, with a male:female ratio of 1.1:1. Seventy-eight of the children (34%) had at least one abnormality in the form of hypertension, decreased eGFR (<90 ml/min/1.73m2) or increased ACR (>30 mg/g) at recruitment. Following re-assessment, 43 of the 78 children had persistent abnormal findings suggestive of early CKD (19%). Factors such as age, sex, type of school, parent’s education, history of family member with kidney disease, and nutritional status were not significantly associated with early CKD.

Conclusion

The outcome of this study indicates that a significant number of school children had persistent abnormal findings suggestive of early CKD. Thus, further emphasising the need for large scale CKD screening programmes in our setting. A long-term follow-up of these children will help determine the clinical significance of these findings and provide more information on the epidemiology of CKD.

Abdullahi Mudi was supported by a VECD Global Health Fellowship, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Fogarty International Center (FIC) of the NIH (D43 TW009337). The views expressed are solely those of the authors and do not necessary represent the views of the NIH.

Funding

  • NIDDK Support