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Kidney Week

Abstract: PO0185

Recovery After AKI: Goals of an AKI!Now Workgroup

Session Information

Category: Acute Kidney Injury

  • 101 AKI: Epidemiology, Risk Factors, and Prevention

Authors

  • Silver, Samuel A., Queen's University, Kingston, Ontario, Canada
  • Abdel-Rahman, Emaad M., University of Virginia, Charlottesville, Virginia, United States
  • Cerda, Jorge, Albany Medical College, Albany, New York, United States
  • Gewin, Leslie S., Vanderbilt University Medical Center, Nashville, Tennessee, United States
  • Neyra, Javier A., University of Kentucky, Lexington, Kentucky, United States
  • Vijayan, Anitha, Washington University in St Louis, St Louis, Missouri, United States
  • Barreto, Erin F., Mayo Clinic Minnesota, Rochester, Minnesota, United States

Group or Team Name

  • AKI!Now
Background

The American Society of Nephrology recently established the AKI!Now initiative. AKI!Now aims to promote excellence in the prevention and treatment of AKI by transforming the delivery of AKI care to improve clinical and patient-centered outcomes. Herein, we describe the focused efforts of AKI!Now on “recovery after AKI.”

Methods

Three core objectives were identified in the domain of AKI recovery:
1. To determine areas of priority for mechanistic research focused on recovery after AKI. It is expected that these would include a variety of experimental models suitable for various AKI etiologies and disease severities.
2. To benchmark existing strategies to care for patients after AKI including integrated insights from primary care providers, nephrologists, other subspecialty health care professionals.
3. To facilitate implementation and testing of interventions designed to limit short- and long-term complications of AKI and promote recovery. Dialysis dependent and independent AKI survivors should both be considered for these interventions and clinical trials.

Results

The AKI!Now initiative will highlight and clarify challenges and opportunities to improve care after AKI. This work will also inform who is followed after AKI and by whom (i.e., primary care and/or nephrology), options for care delivery (i.e., in-person versus telehealth), and potential practices to improve outcomes (i.e., role of ACEi/ARB and SGLT2 inhibitors after AKI, physical/cognitive rehabilitation). The stakeholder relationships formed, including those with patients, healthcare professionals, industry, and academia, will facilitate a collaborative research and practice agenda necessary to understand and outline best practices after AKI.

Conclusion

Survivors of AKI are a high-risk and growing population, and AKI is associated with worse long-term outcomes than an acute myocardial infarction. However, how to care for patients after AKI remains ill-defined with substantial practice variation. This represents an opportunity for the “recovery after AKI” workgroup of AKI!Now to provide leadership by raising awareness and promoting strategies focused on equitable and effective post-AKI care throughout the American Society of Nephrology and wider nephrology community.