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Kidney Week

Abstract: PO0861

Increased Tricuspid Regurgitation Jet Velocity as a Predictor of Acute Decompensated Heart Failure in ESRD Patients on Maintenance Hemodialysis

Session Information

Category: Dialysis

  • 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Park, Youngchan, Kosin University Gospel Hospital, Busan, Busan, Korea (the Republic of)
  • Kim, Ye na, Kosin University Gospel Hospital, Busan, Busan, Korea (the Republic of)
  • Shin, Ho Sik, Kosin University Gospel Hospital, Busan, Busan, Korea (the Republic of)
  • Jung, Yeonsoon, Kosin University Gospel Hospital, Busan, Busan, Korea (the Republic of)
  • Rim, Hark, Kosin University Gospel Hospital, Busan, Busan, Korea (the Republic of)
Background

Many patients with end-stage renal disease (ESRD) on hemodialysis (HD) experience left ventricular hypertrophy and reduced vascular compliance and are likely to develop heart failure (HF). We aimed to determine the hemodynamic factors associated with acute decompensated events among ESRD patients undergoing HD.

Methods

We retrospectively investigated ESRD patients on HD through a medical record review. We excluded patients with significant ischemic heart disease (IHD), percutaneous coronary intervention or coronary artery bypass graft, significant valvular heart disease (VHD), or malignancy. We divided patients into those experience who experienced any admission due to acute decompensated HF (ADHF) and those who did not.

Results

Of the 188 ESRD patients on HD, 87 were excluded, and 101 were enrolled (mean age: 63.7 years, 52.1% male). The ADHF group demonstrated significantly higher tricuspid regurgitation (TR) jet velocity (2.9 ± 0.6 vs. 2.5 ± 0.4 m/s, respectively; p=0.004) than the non-ADHF group. Multivariate logistic regression analysis demonstrated that TR jet velocity (odds ratio: 8.356, 95% confidence interval: 1.806–38.658; p=0.007) was an independent predictor of ADHF after adjusting for age and sex, while LVEF and E/E’ were not. Per receiver operating characteristic curve analysis, TR jet velocity > 2.8 m/s was associated with ADHF with 47.7% sensitivity and 76.4% specificity (area under the curve: 0.656).

Conclusion

Our data showed that increased TR jet velocity was an independent predictor of ADHF events in ESRD patients on HD, but LVEF and E/E’ were not.

Baseline characteristics