Abstract: PO2089
The Impact of COVID-19 on Deceased Donor Renal Transplant Program in a Federal State of South India
Session Information
- Transplantation: Clinical - Allocation, Evaluation, Prognosis, and Viral Onslaughts
November 04, 2021 | Location: On-Demand, Virtual Only
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 1902 Transplantation: Clinical
Authors
- Herur, Siddharth, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India
- Guditi, Swarnalatha, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India
- Kinjarapu, Srinivasa Naidu, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India
- Saigal, Megha, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India
Background
The Covid 19 pandemic has had an impact on all facets of health care system, including organ donation, procurement and transplantation in many countries.India is the country most affected with covid 19 and also the country with a huge waiting list for all solid organ transplants. ESKD is unique that different forms of RRT are available to sustain life. The risk - benefit ratio for delaying elective transplantation during the pandemic is not clear.
Methods
A decsriptive cross sectional study. All the deceased donor solid organ transplantations that took place in the state of Telangana from Jan 2020 to May 2021 were included. Live transplants were excluded. Comparison of the number of transplants of different organs, before and during the pandemic was done. Unpaired t test was used to compare the outcomes between the waitlisted and transplanted group.
Results
The total number of solid organ transplants from deceased donors in the pandemic year of 2020 dropped down to 54% compared to the previous year. Comparison between different organs revealed the maximum decline in number for kidney transplantation (51%), compared to liver (42%), heart (18%) as opposed to 110% increase in lung transplantation. Infectivity rate of covid 19 in the waitlisted group (top 50 in each blood group) registered for deceased renal transplantation is 0.16%. The infectivity rate in the transplanted group (deceased donor renal transplant) during the pandemic in the post transplant period of 6 months is 0.19%. The mortality rate of covid 19 between the two groups is also similar (0.04 in the waitlisted group and 0.06% in the transplanted group). The unpaired t test showed no statistical difference between the two groups.
Conclusion
There is a significant decline in the number of transplantations during the pandemic. Kidney is the most affected organ with 51% decline. Lung transplantation had a 110% rise in numbers during the pandemic. There is no statistical difference of the infectivity rate and mortality rate of covid 19 between waitlisted group and transplanted group of deceased donor renal transplant during the pandemic.
| waitlisted group ( n = 200 ) | transplanted group ( n=166) | p value ( unpaired t test ) | |
| covid 19 infectivity rate | 32/200 = 16 % | 27/166 =16.2 % | < 0.05 |
| covid 19 mortality rate | 11/200 = 5 % | 8/166 = 4.6 % | <0.05 |