Abstract: PUB171
Perineural Cysts in Polycystic Kidney Disease
Session Information
Category: Trainee Case Report
- 1001 Genetic Diseases of the Kidneys: Cystic
Authors
- Amari, Kana R., Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
- Tuazon, Jennifer A., Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
Introduction
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease characterized by cyst formation in the kidneys and other organs. In the nervous system, arachnoid cysts have been found in ~8% of patients with spinal meningeal cysts being far less commonly reported.
Case Description
A 51 y.o. man presented to the Nephrology clinic for ADPKD. He underwent an MRI of the abdomen to calculate his total kidney volume. Incidentally found were multiple T2 hyperintense lesions in the intercostal spaces, most prominent in the left paraspinal midthoracic spine. A dedicated MRI of the thoracic spine was subsequently performed which further characterized the lesions to reflect perineural cysts.
Discussion
Perineural cysts are benign pouches filled with cerebrospinal fluid (CSF) located at the nerve root canals along the spine. Only a few cases of spinal meningeal cysts/perineural cysts have been reported in association with ADPKD. Most cases are asymptomatic, but variable nerve root or spinal cord compression may be present. Low-back pain, radiculopathy, and headache due to cerebrospinal fluid leakage may also occur, thus, such symptoms in a patient with ADPKD should warrant further investigation for this condition.
Perineural cyst in thoracic spine