ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

ASN / Education & Meetings / Kidney Week /

Please note that you are viewing an archived section from 2021 and some content may be unavailable. To unlock all content for 2021, please visit the archives.

Abstract: PO0031

Risk Factors for AKI and Mortality in COVID-19 in Western Mexico

Session Information

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Garcia Rivera, Alejandro, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Katia yuritzi, Ríos Cornejo, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Aguilar, Arantxa Karina, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Villegas Gutierrez, Luz Yareli, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Elias Lopez, Marcos Adrian, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Rico sánchez, Jesús Alejandro, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Morales Guillén, Mónica Lizbeth, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Montemayor Villacobos, Mauro Gerardo, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Villanueva Macedo, Roxana, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Espinoza, Hugo Bonifacio, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Soto Rodriguez, Ramon Angel, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Gutiérrez Hernandez, José Jesús, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Sanchez Vazquez, Omar Humberto, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Topete reyes, Jorge fernando, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Parra Michel, Renato, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Lara Monterrubio, Rubén, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Valdez Avendaño, Mario, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Rios Rios, Fabiola Vanessa, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
  • Alvarez, Carolina Romo, Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Especialidad en Nefrologia, Hospital General Regional No. 46 del IMSS, Guadalajara, Jalisco, Mexico
Background

Acute kidney injury (AKI) in COVID-19 is associated with disease severity. The aim of this study was to identify risk factors associated with the development of AKI and its clinical impact, such as need for RRT and mortality.

Methods

Retrospective cohort study of hospitalized adult patients COVID-19, with normal kidney function, from April to December 2020 in Western Mexico.

Results

882 patients (60.8% men) with a mean age of 58.9y were included. 342 (38.8%) had a prior diagnosis DM, 412 (46.7%) HTN, 161 (18.3%) obesity, 59 (6.7%) heart diseases, 25 (2.8%) neurological disease, 47 (5.3%) lung disease. 216 (24.5%) smoking history. 270 patients (30.6%) developed AKI, 95 (10.77%) KDIGO stage 1, 44 (4.98%) stage 2, and 84 (9.52%) stage 3. 59 patients required RRT (6.23%), and 111 patients (12.6%) mechanical ventilation. Overall mortality was 30.6% (270 patients). Risk factors for mortality were: DM, HTN, neurological disease, age > 65 y, need for MV, and MAP < 65 mmHg, hyperNa, increased D-dimer or decreased HCO3 at admission. Risk factors for AKI were: DM, HTN, heart disease, age > 65 y, need for MV, and MAP < 65 mmHg, hyperNa, increased D-dimer or decreased HCO3 at admission. Image shows risk factors, ORs with CI.

Conclusion

A high incidence of AKI in the Mexican population compared to reports from other countries, with a significantly high risk for death.