Abstract: PO0085
Analysis of the COVID-19 Pandemic in Home and In-Center Dialysis Populations
Session Information
- COVID-19: Health Systems and More
November 04, 2021 | Location: On-Demand, Virtual Only
Abstract Time: 10:00 AM - 12:00 PM
Category: Coronavirus (COVID-19)
- 000 Coronavirus (COVID-19)
Authors
- Cherif, Alhaji, Renal Research Institute, New York, New York, United States
- Wang, Yuedong, University of California Santa Barbara, Santa Barbara, California, United States
- Lasky, Rachel, Fresenius Medical Care North America, Waltham, Massachusetts, United States
- Willetts, Joanna, Fresenius Medical Care North America, Waltham, Massachusetts, United States
- Usvyat, Len A., Fresenius Medical Care North America, Waltham, Massachusetts, United States
- Kotanko, Peter, Renal Research Institute, New York, New York, United States
Background
While dialysis patients have a high risk of complications from COVID-19, in-center hemodialysis (ICHD) patients show lower SARS-CoV-2 reproduction rates when compared to the general population (Cherif, JASN 2021), possibly related to lifestyle and interventions to prevent SARS-CoV-2 spread. Here we expand the research to study the prevalence of COVID-19 in both home (PD/HHD) and ICHD patients.
Methods
We analyzed COVID-19 cases in PD/HHD and ICHD patients from the U.S. Fresenius Kidney Care (FKC) network, from March 1 to November 27, 2020. Patients were tested for SARS-CoV-2 (confirmed by RT-PCR) when showing signs compatible with COVID-19 or exposed to an infected person. We perform statistical analysis for inter-/intra-modalities, with continuous and categorical variables being expressed as the mean (standard deviation) and absolute (relative, %), respectively.
Results
We studied 263,223 patients (age 62.8±14.5 years, 57.7% males) receiving dialysis in the FKC network (87.3% ICHD; 12.7% PD/HHD). In the FKC network, 21,175 (8.05%) were infected with SARS-CoV-2. COVID-19 infection was more prevalent among ICHD (8.56%) vs. PD/HHD (4.49%) patients. Black had a significantly higher risk than other races for both ICHD (9.10%, p < 0.0001) and PD/HHD (5.13%, p = 0.0038), without a difference between modalities (p = 0.1827). While white ICHD patients did not have a different risk compared to others (8.52%, p = 0.4105), they had a smaller risk when dialyzed at home PD/HHD (3.82%, p < 0.0001), and the difference between ICHD and PD/HHD was significant (p < 0.0001). Similar results are shown for other patients (Tab.1).
Conclusion
COVID-19 infection was more common among ICHD patients. To what extent this is related to lifestyle, travel to dialysis facilities or other aspects warrants further analyses.
Funding
- NIDDK Support