Abstract: INFO11
GUDMAP: The GenitoUrinary Development Molecular Anatomy Project
Session Information
- Informational Posters
November 04, 2021 | Location: On-Demand, Virtual Only
Abstract Time: 10:00 AM - 12:00 PM
Category: Development, Stem Cells, and Regenerative Medicine
- No subcategory defined
Author
- Valerius, M. Todd, Brigham and Women's Hospital, Boston, Massachusetts, United States
Group or Team Name
- The GUDMAP Consortium
Description
The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an open access online resource developed by a consortium of laboratories working to provide the scientific and medical community with transcriptomic and protein expression data, high-resolution 2D and 3D morphological data, and tools to facilitate research and teaching in genitourinary (GU) system. Data encomposes developmental time points and the adult, and includes mouse, canine, and human tissue sources. The goal is to stimulate further research into the genitourinary system by identifying novel cell types and gene expression domains in the kidneys, ureters, bladder, prostate, urethra, external genitalia, and associated reproductive structures and accompanying innervation. The GUDMAP database includes data from large-scale in situ hybridization screens, RNA-seq and scRNA-seq and microarray gene expression data, ChIP-seq, 3D Optical Projection Tomography (OPT) images, nanoscale computed tomography (nanoCT) image volumes, immunofluorescence, and high-resolution histology of the developing mouse and human GU system. Beyond tissue structures, GUDMAP includes characterization of nociceptors and associated cell types in pain processing of the murine urinary tract and pelvic region. Expression data and histological samples are annotated using a high-resolution ontology specific to the GU system. The database is searchable by gene name, function, or anatomical structure, leading users to available annotated datasets including scRNA-seq data. GUDMAP data are curated and accessible at www.gudmap.org.
GUDMAP is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
www.gudmap.org
Funding
- GUDMAP is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).