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Abstract: FR-PO844

The Impact of Kidney Transplantation on Systolic and Diastolic Blood Pressure and the Number of Blood Pressure Medications in the First Year Post Kidney Transplantation

Session Information

Category: Transplantation

  • 2002 Transplantation: Clinical

Authors

  • Arabi, Ziad, Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Abdulgadir, Mohamad Yousif, Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Youssouf, Talha Mohammad, Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Althani, Abdullah Saleh, Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Alhamzah, Hamzah Ali, Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Alhejaili, Fayez F., Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Elhassan, Elwaleed A., Division of Nephrology, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Background

To examine the impact of kidney transplantation ( KT) on systolic (SBP) and diastolic blood pressure (DBP) and the number of blood pressure (BP) medications in the first-year post-kidney transplantation at our center.

Methods

This is a single center retrospective study of renal transplant recipients who underwent KT between January 2017 and May 2020 with 12 months follow up. The BP target goal at the time of this retrospective study was <140/90 mm Hg.
We reviewed BP readings before and at one, 6, and 12 months after kidney transplantation. We also reviewed the number of BP medications at the same intervals post transplantation.

Results

A total of 278 renal transplant recipients were included. Of those, 74% were ≥ 30 years of age, 58% were men and 80% were living-donor kidney recipients. Preemptive transplantation was 10.1%, PD 11.5% and HD 78.4% respectively.
At one year, 70.1% of patients attained the target BP goal. SBP was 138.6±22.3 at baseline and it improved by -6.51 (-9.62 to -3.4) by 12 months (P<0.001). DBP was 77.6±15.1 at baseline and it improved by -5.25 (-7.5 to -3) by 12 months (P<0.001). {Figure.1} These changes were observed in both genders and at a comparable difference (P=0.579 for SBP, P=0.136 for DBP).
The number of blood pressure medications also significantly decreased. {Figure.2}

Conclusion

Our study demonstrated the positive effect of kidney transplantation on systolic and diastolic blood pressures in the first-year post transplantation in both genders. The number of BP medications also significantly decreased.