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Abstract: TH-PO892

Factors Associated With Influenza Non-Vaccination Among Patients With CKD Under Nephrology Care

Session Information

Category: CKD (Non-Dialysis)

  • 2201 CKD (Non-Dialysis): Epidemiology‚ Risk Factors‚ and Prevention

Authors

  • Ishigami, Junichi, Johns Hopkins University, Baltimore, Maryland, United States
  • Jaar, Bernard G., Johns Hopkins University, Baltimore, Maryland, United States
  • Lash, James P., University of Illinois Chicago, Chicago, Illinois, United States
  • Brown, Julia, University of Illinois Chicago, Chicago, Illinois, United States
  • Chen, Jing, Tulane University, New Orleans, Louisiana, United States
  • Mills, Katherine T., Tulane University, New Orleans, Louisiana, United States
  • Taliercio, Jonathan J., Cleveland Clinic, Cleveland, Ohio, United States
  • Charleston, Jeanne, Johns Hopkins University, Baltimore, Maryland, United States
  • Kansal, Sheru, University Hospitals, Cleveland, Ohio, United States
  • Crews, Deidra C., Johns Hopkins University, Baltimore, Maryland, United States
  • Riekert, Kristin, Johns Hopkins University, Baltimore, Maryland, United States
  • Dowdy, David W., Johns Hopkins University, Baltimore, Maryland, United States
  • Appel, Lawrence J., Johns Hopkins University, Baltimore, Maryland, United States
  • Matsushita, Kunihiro, Johns Hopkins University, Baltimore, Maryland, United States
Background

Influenza vaccines are strongly recommended in patients with CKD due to their high risk of poor outcomes. Identifying risk factors for not receiving an influenza vaccine (“non-vaccination”) could inform strategies for improving vaccine uptake in this population.

Methods

We explored factors associated with influenza non-vaccination in 3522 CRIC participants (mean age 66 years, 43% female, 44% Black). Receipt of influenza vaccine was asked during annual clinic visits in 2008-2020 (median, 4 times per person) if participants were seen by a nephrologist, and assessed along with age, sex, race, diabetes, COPD, eGFR, urine protein-to-creatinine ratio, education, household income, marital status, employment status. We used mixed-effects Poisson models to estimate adjusted prevalence ratios (aPRs) for association with non-vaccination.

Results

The overall vaccine uptake was 72%. Factors significantly associated with influenza non-vaccination were younger age (aPR, 2.18 [95%CI, 1.85-2.56] for <50 vs. 75+ years), Black race (1.57 [1.41-1.74] vs. White), lower education, lower annual household income, formerly married status, and non-employed status (Figure). Participants with diabetes (0.80 [0.72-0.88]) and COPD (0.80 [0.70-0.93]) were more likely to receive vaccination than those without. Those with ESKD were more likely to receive vaccination (0.66 [0.56-0.79] vs. eGFR 60+ ml/min/1.73m2).

Conclusion

Despite nephrology care, influenza vaccines were underutlized for CKD patients, particularly younger adults, Black individuals, and those with low socioeconomic status. Strategies to improve vaccine uptake through nephrology care should be explored in future studies.

Funding

  • NIDDK Support