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Abstract: TH-PO076

Pregnancy Associated AKI: An 8-Year Study From South India

Session Information

Category: Acute Kidney Injury

  • 102 AKI: Clinical‚ Outcomes‚ and Trials

Authors

  • Bantewad, Devidas Shankar, Gandhi Hospital, Secunderabad, Telangana, India
  • Yadla, Manjusha, Gandhi Hospital, Secunderabad, Telangana, India
Background

Pregnancy-related acute kidney injury (PRAKI) is a major cause of maternal and fetal morbidity and mortality in developing countries. With improvement in antenatal and postnatal care, the incidence of PRAKI in India has steadily declined from 22% in 1960s to 9% in 1980s, and further down to 3–7% in 2000s.

Methods

Aim : To study the clinical characteristics and outcomes of patients with PRAKI
Design : Prospective observational study
Setting : Tertiary Care Government Hospital in Telangana
Period of study : Jan 2014 to May 2022
Methodology : Data collected prospectively from All admitted pregnant and postpartum patients who developed a PRAKI.
Inclusion criteria : All pregnant and postpartum patients who developed a PRAKI.
Exclusion criteria : 1. Evidence of renal disease prior to pregnancy
2. Elevated serum creatinine prior to gestation

Results

A total of 311 patients satisfied inclusion criteria.
Pregnancy related Acute Kidney Injury was 0.32% of total pregnancies in our institute.
The Institutional incidence of pregnancy related Acute Kidney Injury in context of all cases of AKI was 5.88%, out of which dialysis requiring PRAKI incidence was 4.22% at our institute.

Conclusion

1. Incidence of pregnancy related Acute kidney injury in context of overall AKI was 5.88%
2. Most common cause of PRAKI in our study was preeclampsia (43.4%)
3. Sepsis and multisystem involvement was in 74.27 and 21.86% patients respectively.
4. In our institute Maternal mortality was 21.54% and fetal mortality was 47.58%.
5. Total patients receiving RRT was 223 (71.70%) while 88 (28.29%) patients was managed conservatively.

RESULTS TABLES

RESULTS TABLES