Basic/Clinical Science Session
Progenitor Programs Directing Development of Human Kidneys
October 22, 2026 | 10:30 AM - 12:30 PM
Location: Mile High Ballroom 4D, Convention Center
Session Description
An understanding of human development informs efforts to generate functional human kidney cell types. Interactions among distinct progenitors drive human kidney development. This session highlights nephron and ureteric progenitors of the kidneys' nephron and collecting system, respectively. Speakers discuss molecular and cellular mechanisms that regulate kidney progenitor programs and apply insights to differentiate functional human kidney cells. A developmental mechanism-informed framework is broadly applicable to replicating the diversity of human kidney cell types.
Learning Objective(s)
- Explain how progenitors are distinguished from stem cells
- Describe which genetic strategies have identified mammalian kidney progenitor types
- Summarize how single-cell technologies advanced the view of kidney cell diversity
Learning Pathway(s)
- Genetic Diseases and Development
- Pediatric Nephrology
Moderators
Presentations
- Rhythmic Recruitment of Nephron Progenitors to the Nephrogenic Program
10:30 AM - 11:00 AM
- Tuning Nephron Differentiation in Human Kidney Organoid Models
11:00 AM - 11:30 AM
- Optimized Differentiation of Functional Nephron Cell Types in Human Kidney Organoid Models
11:30 AM - 12:00 PM
- Human Organoid-Directed Differentiation of Functional Collecting Epithelium
12:00 PM - 12:30 PM