Basic/Clinical Science Session
Cytoskeletons Lurking in the Closet: Cell Biology Mediating CKD Progression
October 22, 2026 | 02:00 PM - 04:00 PM
Location: Room 107, Convention Center
Session Description
The cell cytoskeleton does more than provide a cellular scaffold in dynamic environments. This session examines how modulators of the cell cytoskeleton and mechanosensors can facilitate regeneration or promote further injury, thereby contributing to CKD progression after cellular stressors. Cutting-edge research is presented that elucidates how the cytoskeleton can uniquely alter mitochondrial function and affect proteinuria-mediated tubular injury, as well as the roles of podocyte mechanosensors and novel models of biomechanical forces in defining responses to kidney injury.
Learning Objective(s)
- Define how changes in the cell cytoskeleton affect mitochondria and responses to injury
- Describe how mechanosensors (e.g., YAP/TAZ) alter podocyte responses to stress and injury
- Explain the role of actin cytoskeleton in mediating proteinuria-induced tubular injury
Learning Pathway(s)
- CKD Non-Dialysis
- Kidney Biology and Physiology
Moderators
Presentations
- Role of Rac1 in Proximal Tubule Repair
02:00 PM - 02:30 PM
- Proteinuria-Induced Changes in Tubular Actin Cytoskeleton and Cilia
02:30 PM - 03:00 PM
- Mechanosensors in Renal Urothelium Promote Remodeling After Obstruction
03:00 PM - 03:30 PM
- YAP/TAZ Overactivity and CKD Progression
03:30 PM - 04:00 PM