Basic/Clinical Science Session
New Frontiers in Kidney Stone Diseases
October 24, 2026 | 02:00 PM - 04:00 PM
Location: Room 405, Convention Center
Session Description
Human urine is often supersaturated, and kidney stones are common. Recent studies have improved our understanding of the factors that drive this supersaturation and modify the risk of kidney stone formation. Our understanding of monogenic and polygenic risks continues to expand. Recent evidence highlights the role of the gastrointestinal microbiome in modifying the absorption of key lithogenic molecules. This session describes the current understanding of liver pathways involved in oxalate generation and intrarenal inflammatory-cell responses to crystals, which are potential treatment targets.
Learning Objective(s)
- Identify key oxalate-degrading gut bacteria
- Identify new and established genetic causes of kidney stones
- Describe oxalate-generating pathways and how they can be manipulated
- Describe inflammatory mechanisms relevant to crystal retention in the kidneys
Learning Pathway(s)
- Bones‚ Stones‚ and Mineral Metabolism
Moderators
Presentations
- Gastrointestinal Oxalobiome in Health and Disease
02:00 PM - 02:30 PM
- Genetics in the Stone Clinic: Bench to Bedside
02:30 PM - 03:00 PM
- Hepatic Oxalate Generation and Strategies to Manipulate It
03:00 PM - 03:30 PM
- Inflammatory Neighborhoods and Crystal Retention
03:30 PM - 04:00 PM