ADPKD and Cystic Kidney Disease - 1
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Posters
ADPKD and Cystic Kidney Disease - 1
October 22, 2026 | 10:00 AM - 12:00 PM
Location: Exhibit Hall A, Convention Center
Session Description
Poster Session
Posters
Small-Molecule Correction of Trafficking-Defective PKD1 Variants Restores Ciliary Polycystin-1 Localization in ADPKD
Decreased Branched-Chain Amino Acids (BCAAs) Catabolism Is Important for mTORC1 Activation and Cystogenesis in ADPKD
Reduced Cholesterol as a Potential Mechanism of Phenotypic Convergence for PKD1 and PKD2 Variants
Real-World Outcomes of GLP-1 Receptor Agonist Therapy in Nondiabetic ADPKD: Effects on Mortality and Progression to ESRD in a TriNetX Cohort
In Vivo Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Screening Identifies Epigenetic Regulation of Intrinsic Immunogenicity in ADPKD
Loss of Polycystin-1 Increases DCLK1 Expression in Intestinal Epithelia and Is Regulated by the GPR109A Receptor
Collecting Duct-Targeted Dual-siRNA Micelles Attenuate ADPKD
The CKD Hierarchical Composite End Point (HCE) in ADPKD
Evaluation of TMEM67 Haploinsufficiency as a Cause or Modifier of ADPKD
Interplay Between Primary Cilia and Integrin β1 Signaling in Kidney Maintenance
Genotype-Phenotype Correlations in an ADPKD Population in the All of Us Cohort
Exon-Level Distribution and Clustering of Variants of Uncertain Significance in ADPKD
Genomic Landscape of ADPKD: Towards Precision Diagnostics
Kidney-Targeted Lipid Nanoparticle-Delivered Clustered Regularly Interspaced Short Palindromic Repeats (LNP-CRISPR) Gene Editing as a Mutation-Agnostic, Single-Intervention Therapeutic Strategy for ADPKD
Resolvin D1 Inhibits cAMP/PKA Signaling Through Formyl Peptide Receptor 2 Activation and Slows PKD Progression
Periostin-Integrin Signaling Orchestrates Inflammation and Fibrosis in ADPKD
Chemical Chaperones Improve PC1 Ciliary Trafficking and Rescue the Cystic Phenotype in ADPKD Mouse Three-Dimensional (3D) Spheroids
Asparagine Synthetase (ASNS) Is the Primary Regulator of Glutamine Use Supporting Reductive Carboxylation in PKD
Targeting Runx1 Slows Cyst Growth in ADPKD
Gene-Based Rare Variant Associations Identify Known and Candidate Loci in Polycystic Kidney Disease Across Population-Scale Cohorts
Factors Associated with Kidney Failure in a Large Population of Patients with ADPKD and PKD1 Truncating Variants: A Multicenter Study
ADPKD-Associated Risk of Incident and Recurrent Urinary Tract Infection
Concepts of Importance to Patients with ADPKD and Psychometric Validity of Corresponding Clinical Outcome Assessments (COAs): A Targeted Literature Review (TLR)
Clinical Characteristics of ADPKD in Thailand
Real-World Experience with Panel Genetic Testing in Clinical Nephrology
Spatially Resolved Microenvironmental Changes in Tubules at Early Cystogenesis in an mTOR-Overactivated Polycystic Kidney Disease Mouse Model
Comprehensive Plasma Proteomic Profiling Reveals Immune, Inflammatory, and Extracellular Matrix Dysregulation in ADPKD
Plasma Metabolomic Profiling Identifies Distinct Lipid and Energy-Metabolism Signatures in ADPKD
A Metabolomic Analysis of ADPKD Dietary Intervention Trials
Cyst-Type Epithelial Heterogeneity Shapes Therapeutic Responsiveness in ADPKD
Development of an Artificial Intelligence (AI) Pipeline to Mechanistically Decipher Signaling Crosstalk and Predict Synergistic Combinations in ADPKD
Practice Patterns in Native Nephrectomy for ADPKD: A Cross-Sectional Survey of US Clinicians
Internal Validation of Quantitative Variant Scores for ADPKD Pathogenicity Classification
Epithelial Pregnancy-Associated Plasma Protein A and Circulating Insulin-Like Growth Factor Binding Protein 4 Fragments Indicate Insulin-Like Growth Factor Axis Dysregulation in ADPKD
Downregulation of Bone Morphogenetic Protein (BMP) Signaling Promotes ADPKD Progression
Association of Mayo Classification with Severity of Vascular Dysfunction in ADPKD
Functional Investigation of Notch3 Dysregulation in ADPKD Indicates Vasculature Involvement
CP6 Regulates Autophagy Through Integrin-AKT Signaling in Polycystic Kidney Disease
Predicting ADPKD Progression via Cyst Tracking
Federated Clinical and Genetic Analysis of International ADPKD Cohorts Using the Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP)
Preclinical Safety and Pharmacokinetic Characterization of Oral 2-Deoxyglucose Supporting First-in-Human Trial Design in ADPKD
A Unique Case of Atypical ADPKD with Multicystic Gene Variants
Removal of FPCIP in Renal Tubules Leads to a Predominantly Fibrotic Phenotype
Apelinergic System Signaling Is Altered in Human ADPKD Cell Lines
Patient Journey and Lived Experiences of People Living with ADPKD
Intracranial Aneurysm Prevalence and Risk Factors in ADPKD: A Single-Center Analysis
Global Proteomics Identifies Early-Stage Alterations in Human Tissue Samples of ADPKD
Peripheral Microvascular Endothelial Dysfunction Is Associated with Kidney Structural Disease Severity in Individuals with Early ADPKD
Genotype-Specific Cardiac Phenotypes in ADPKD
Role of Aurora Kinase A in Polycystic Kidney Disease
Scoping Review of Clinical Trial Outcomes in Patients with ADPKD
Disease Progression in Patients Diagnosed with ADPKD by Variant Subgroups in HALT-PKD and CRISP
Guanine Quadruplex-Based Genome Instability and Polycystin Disruption in ADPKD
RNA Structure and Protein Interactome Mapping of PKD1 Identifies Targetable Post-Transcriptional Regulators in ADPKD
Dual PKD1/ALG5 Variants Presenting as Atypical ADPKD: A Case Report
Intravital Two-Photon Imaging Reveals an Early Proximal-Tubule Endocytic Deficiency in Pkd1 Haploinsufficient Mouse Kidneys
Unexpectedly Mild Adult-Onset ADPKD in Patients with Digenic Hypomorphic PKD1 and Truncating PKD2 Variants
Exploring the Regulation of PKD1-Mediated G-Protein Signaling
Longitudinal Intravital Imaging Reveals Epithelial Proliferation and Impaired Fluid Clearance During Early Cyst Expansion in Pkd1 Kidneys
Multifaceted Comparative PKD1/PKD2 Missense Variant Profiling Improves ADPKD Molecular Diagnosis and Reveals a Common Pathomechanism/Disease Determinant and Variant Complexity
HTD1801 Suppresses Cyst Expansion in PKD1-Mutant Nephron Organoids: Evidence for AMPK-NLRP3 Axis Efficacy in ADPKD
GRK6 Promotes PKD1 Trafficking to Primary Cilia
Largest Reported TSC2/PKD1 Contiguous Gene Deletion Syndrome (CGS) with Additional Deletion of IFT140
Using a Diphtheria Toxin (DT)-Based Genome Engineering Approach ("Xential") for Functional Analysis of PKD1 and PKD2
Small-Molecule Correction of Trafficking-Defective PKD1 Variants Restores Ciliary Polycystin-1 Localization in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Decreased Branched-Chain Amino Acids (BCAAs) Catabolism Is Important for mTORC1 Activation and Cystogenesis in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Reduced Cholesterol as a Potential Mechanism of Phenotypic Convergence for PKD1 and PKD2 Variants
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Real-World Outcomes of GLP-1 Receptor Agonist Therapy in Nondiabetic ADPKD: Effects on Mortality and Progression to ESRD in a TriNetX Cohort
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
In Vivo Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Screening Identifies Epigenetic Regulation of Intrinsic Immunogenicity in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Loss of Polycystin-1 Increases DCLK1 Expression in Intestinal Epithelia and Is Regulated by the GPR109A Receptor
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Collecting Duct-Targeted Dual-siRNA Micelles Attenuate ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
The CKD Hierarchical Composite End Point (HCE) in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Evaluation of TMEM67 Haploinsufficiency as a Cause or Modifier of ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Interplay Between Primary Cilia and Integrin β1 Signaling in Kidney Maintenance
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Genotype-Phenotype Correlations in an ADPKD Population in the All of Us Cohort
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Exon-Level Distribution and Clustering of Variants of Uncertain Significance in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Genomic Landscape of ADPKD: Towards Precision Diagnostics
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Kidney-Targeted Lipid Nanoparticle-Delivered Clustered Regularly Interspaced Short Palindromic Repeats (LNP-CRISPR) Gene Editing as a Mutation-Agnostic, Single-Intervention Therapeutic Strategy for ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Resolvin D1 Inhibits cAMP/PKA Signaling Through Formyl Peptide Receptor 2 Activation and Slows PKD Progression
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Periostin-Integrin Signaling Orchestrates Inflammation and Fibrosis in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Chemical Chaperones Improve PC1 Ciliary Trafficking and Rescue the Cystic Phenotype in ADPKD Mouse Three-Dimensional (3D) Spheroids
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Asparagine Synthetase (ASNS) Is the Primary Regulator of Glutamine Use Supporting Reductive Carboxylation in PKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Targeting Runx1 Slows Cyst Growth in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Gene-Based Rare Variant Associations Identify Known and Candidate Loci in Polycystic Kidney Disease Across Population-Scale Cohorts
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Factors Associated with Kidney Failure in a Large Population of Patients with ADPKD and PKD1 Truncating Variants: A Multicenter Study
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
ADPKD-Associated Risk of Incident and Recurrent Urinary Tract Infection
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Concepts of Importance to Patients with ADPKD and Psychometric Validity of Corresponding Clinical Outcome Assessments (COAs): A Targeted Literature Review (TLR)
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Clinical Characteristics of ADPKD in Thailand
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Real-World Experience with Panel Genetic Testing in Clinical Nephrology
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Spatially Resolved Microenvironmental Changes in Tubules at Early Cystogenesis in an mTOR-Overactivated Polycystic Kidney Disease Mouse Model
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Comprehensive Plasma Proteomic Profiling Reveals Immune, Inflammatory, and Extracellular Matrix Dysregulation in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Plasma Metabolomic Profiling Identifies Distinct Lipid and Energy-Metabolism Signatures in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
A Metabolomic Analysis of ADPKD Dietary Intervention Trials
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Cyst-Type Epithelial Heterogeneity Shapes Therapeutic Responsiveness in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Development of an Artificial Intelligence (AI) Pipeline to Mechanistically Decipher Signaling Crosstalk and Predict Synergistic Combinations in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Practice Patterns in Native Nephrectomy for ADPKD: A Cross-Sectional Survey of US Clinicians
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Internal Validation of Quantitative Variant Scores for ADPKD Pathogenicity Classification
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Epithelial Pregnancy-Associated Plasma Protein A and Circulating Insulin-Like Growth Factor Binding Protein 4 Fragments Indicate Insulin-Like Growth Factor Axis Dysregulation in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Downregulation of Bone Morphogenetic Protein (BMP) Signaling Promotes ADPKD Progression
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Association of Mayo Classification with Severity of Vascular Dysfunction in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Functional Investigation of Notch3 Dysregulation in ADPKD Indicates Vasculature Involvement
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
CP6 Regulates Autophagy Through Integrin-AKT Signaling in Polycystic Kidney Disease
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Predicting ADPKD Progression via Cyst Tracking
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Federated Clinical and Genetic Analysis of International ADPKD Cohorts Using the Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP)
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Preclinical Safety and Pharmacokinetic Characterization of Oral 2-Deoxyglucose Supporting First-in-Human Trial Design in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
A Unique Case of Atypical ADPKD with Multicystic Gene Variants
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Removal of FPCIP in Renal Tubules Leads to a Predominantly Fibrotic Phenotype
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Apelinergic System Signaling Is Altered in Human ADPKD Cell Lines
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Patient Journey and Lived Experiences of People Living with ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Intracranial Aneurysm Prevalence and Risk Factors in ADPKD: A Single-Center Analysis
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Global Proteomics Identifies Early-Stage Alterations in Human Tissue Samples of ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Peripheral Microvascular Endothelial Dysfunction Is Associated with Kidney Structural Disease Severity in Individuals with Early ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Genotype-Specific Cardiac Phenotypes in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Role of Aurora Kinase A in Polycystic Kidney Disease
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Scoping Review of Clinical Trial Outcomes in Patients with ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Disease Progression in Patients Diagnosed with ADPKD by Variant Subgroups in HALT-PKD and CRISP
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Guanine Quadruplex-Based Genome Instability and Polycystin Disruption in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
RNA Structure and Protein Interactome Mapping of PKD1 Identifies Targetable Post-Transcriptional Regulators in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Dual PKD1/ALG5 Variants Presenting as Atypical ADPKD: A Case Report
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Intravital Two-Photon Imaging Reveals an Early Proximal-Tubule Endocytic Deficiency in Pkd1 Haploinsufficient Mouse Kidneys
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Unexpectedly Mild Adult-Onset ADPKD in Patients with Digenic Hypomorphic PKD1 and Truncating PKD2 Variants
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Exploring the Regulation of PKD1-Mediated G-Protein Signaling
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Longitudinal Intravital Imaging Reveals Epithelial Proliferation and Impaired Fluid Clearance During Early Cyst Expansion in Pkd1 Kidneys
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Multifaceted Comparative PKD1/PKD2 Missense Variant Profiling Improves ADPKD Molecular Diagnosis and Reveals a Common Pathomechanism/Disease Determinant and Variant Complexity
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
HTD1801 Suppresses Cyst Expansion in PKD1-Mutant Nephron Organoids: Evidence for AMPK-NLRP3 Axis Efficacy in ADPKD
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
GRK6 Promotes PKD1 Trafficking to Primary Cilia
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Largest Reported TSC2/PKD1 Contiguous Gene Deletion Syndrome (CGS) with Additional Deletion of IFT140
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.
Using a Diphtheria Toxin (DT)-Based Genome Engineering Approach ("Xential") for Functional Analysis of PKD1 and PKD2
October 22, 2026 | 10:00 AM - 12:00 PM
Please note that times are exported as Coordinated Universal Time (UTC). Time zone help.