Posters
CKD: Mechanisms of Injury and Fibrosis - 1
October 22, 2026 | 10:00 AM - 12:00 PM
Location: Exhibit Hall A, Convention Center
Session Description
Poster Session
Posters
Role of Mitochondrial Dysfunction in the Progression of CKD in Obesity-Induced Hyperlipidemia
SerpinA3k Deficiency Protects Against Kidney Fibrosis Through Preservation of the PPARα-Cyp4A14 Axis
Nuclear FAM3A Alleviates Renal Fibrosis via the PURB-PPARα Axis to Regulate Fatty Acid Metabolism
Transient MOTS-c Surge Unmasks Impaired Mitochondrial Stress Signaling in Human Renovascular Disease
Orphan Nuclear Receptor NR4A2 Facilitates Ferroptosis in Renal Tubular Cells by Promoting Degradation of Mitochondrial GPX4
SLC6A19 Inhibition Drives a Protective Proximal Tubule Metabolic State Complementary to SGLT2 Inhibition
Mitochondrial ROS-Driven Ferroptosis via the Cystine/Glutamate Antiporter (xCT)-Glutathione (GSH) Axis in Unilateral Ureteral Obstruction
Phosphate Activates Carbohydrate Responsive Element-Binding Protein via Redox-Dependent Glycerol-3-Phosphate Production
Multisubstrate Tracing Reveals Defective Lactate and Acetate Oxidation in Mouse Renal Cortex in Adenine-Induced Nephropathy
Activation of α7 Nicotinic Acetylcholine Receptor in Fibroblasts Suppresses Renal Fibrosis via HO-1-Mediated Redox Regulation
Critical Role of Transcription Factor PU.1 in Regulating NLRP3 Inflammasome Signaling in Kidney Fibrosis
Palmitoyltransferase DHHC9 Inhibits Macrophage TSP1 Secretion and Suppresses Renal Fibrosis
Tubular PCK1 Defines a Stage-Dependent HNF4A Metabolic Program During Acute and Chronic Kidney Injury
B Cell-Intrinsic Toll-Like Receptor 7 Signaling Drives Tertiary Lymphoid Structures Formation in Injured Kidneys
ST2 Signaling Drives Gut-Immune-Kidney Axis via Mitochondrial Reprogramming and Microbial Remodeling in Chronic Kidney Injury
Spatially Restricted C3-LRP1 Axis Links Tubular Injury to Kidney Fibrosis
Disulfiram Attenuates Adenine-Induced Kidney Injury Through Modulation of Inflammatory and Metabolic Pathways
Scavenger Receptor Splice Variant SR-BII Facilitates High-Fat Diet (HFD)-Induced Kidney and Liver Fibrosis Through Increased Peripheral Inflammation
Tissue-Dependent Opposing Effects of MicroRNA-204 on Hypertension and Kidney Injury
Hematopoietic Mosaic UTY Deficiency on the Y Chromosome Worsens Kidney Failure in Experimental Mice Model
Activated Interstitial Cells May Contribute to NBL1 Induction in Kidney Injury via TGF-β-Smad Signaling
Role and Mechanism of the IRF8-Integrin β8 Signaling Pathway in Renal Tubular Epithelial Cells in Diabetic Kidney Disease
Balcinrenone, a Nonsteroidal Mineralocorticoid Receptor Antagonist, Attenuates Renal Fibrosis Through Modulation of TGF-β-Smad Signaling
Targeting TRPM3 Channels Attenuates Renal Fibrosis by Influencing Maladaptive Repair State of Tubular Cells
Proximal Tubular ALOX5 Links Extracellular Matrix Homeostasis and Collagen Remodeling in Renal Fibrosis
Tubular Mst1 Deletion Aggravates Tubular Cell Apoptosis and Renal Fibrosis via Non-YAP Mechanisms
Development of CKD of Unknown Etiology After AKI: Use of Serum Proteomics to Distinguish Disease Progression from Nonprogression
Truncated Form of Angiotensin-Converting Enzyme 2 with Extended Duration of Action Effectively Reduces Kidney Angiotensin II in a Renin-Transgenic Mouse Model of Scleroderma Kidney
Primary Cilia Couple Host-Pathogen Sensing to CKD Progression
Transcriptomic Profiling of Human Kidney Biopsies Reveals Distinct Mechanisms in Diabetic Nephropathy with and Without HIV Infection Compared with HIV-Associated Nephropathy (HIVAN)
Depalmitoylase ABHD17B Promotes Vascular Smooth Muscle Cell Calcification in CKD Through Interaction with BRG1
Hepatic Hepcidin Deficiency Drives Iron-Mediated Renal Ferroptosis and Chronic Kidney Injury
Cross-Species Single-Cell and Spatial Profiling of Kidney Macrophage Identifies Conserved GPNMB+ Lipid-Associated Macrophages Linked to Kidney Fibrosis
Fn14 Mediates Failed Epithelial Repair in Repeated Low-Dose Cisplatin Nephrotoxicity
TRIM16 Facilitates Autophagy Activation and Renal Fibrosis by Promoting Ubiquitin-Mediated Degradation of S2448-Phosphorylated mTOR
Renal Reserve Assessment by Transdermal Fluorescence Detection: An In Vivo Porcine Model
Indoxyl Sulfate Promotes Uremic Arterial and Venous Thrombosis via SHFM3-Mediated Stabilization of Indoleamine 2,3-Dioxygenase 1
Bifidobacterium longum BB536 Ameliorates Kidney Dysfunction and Alters Gut Microbiota in an Adenine-Induced CKD Mouse Model
Myeloid TLR4 Signaling Promotes the AKI-to-CKD Transition by Inducing Trained Immunity
5-HT2B Antagonism Reduces Renal Cortical Fibrosis and Restores Kidney Function in an Adenine-Induced CKD Rat Model
Novel Insights into the Interplay Between Ferroptosis and PANoptosis Under Uremic Toxin Stress in the Progression of CKD
Endothelial Angiopoietin-2 Contributes to Early but Not Late Kidney Injury After Unilateral Ureteral Obstruction
Value of 5.0T Multiparametric MRI in Assessment of Renal Fibrosis in Patients with CKD
Daily Repeated Optogenetic Vagus Nerve Stimulation Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction
XTL6001: A Novel Triple MasR/GCGR/GLP-1 Receptor Agonist for Hyperuricemic Nephropathy
Chain-Length-Specific Ceramide Remodeling in CKD and Its Hepatic Drivers
Pharmacologic Inhibition of Ceramide Synthases Ameliorates Adriamycin-Induced Kidney Injury and Suppresses Pathogenic C16 Ceramide Accumulation
Reversible Iron Chelation and Iron Restriction Attenuate Ferroptosis and Kidney Fibrosis in CKD Mouse Models
Preclinical Evaluation of GENC-231, a Selective NUAK1 Inhibitor, for Kidney Fibrosis
Roxadustat-Preconditioned Mesenchymal Stem Cells Ameliorate Kidney Inflammation and Fibrosis Through STC1-Mediated NF-κB/NLRP3 Suppression
Urinary Extracellular Vesicle Proteomics Reveals Inflammatory and Early Fibrotic Kidney Signatures in People with HIV
Cardiac LIM Protein Attenuates TGF-β Signaling While Driving Proliferation and Maladaptive Repair in Injured Proximal Tubule
Flow Cytometry Identifies CD45-PDGFRβ+ Stromal Cells as a Collagen I-Enriched Population in Unilateral Ureteral Obstruction Kidney Fibrosis