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Kidney Week

Abstract: TH-PO621

Correlates of Physical Inactivity Across Kidney Disease Stages: An Observational Multicentre Study

Session Information

Category: Health Maintenance, Nutrition, and Metabolism

  • 1300 Health Maintenance, Nutrition, and Metabolism


  • Wilkinson, Thomas James, University of Leicester, Leicester, United Kingdom
  • Clarke, Amy Louise, University College London, London, United Kingdom
  • Nixon, Daniel, University of Leicester, Leicester, United Kingdom
  • Hull, Katherine Leigh, University Hospitals of Leicester NHS Trust, Coventry, United Kingdom
  • Burton, James, University of Leicester, Leicester, United Kingdom
  • Smith, Alice C., University of Leicester, Leicester, United Kingdom

Group or Team Name

  • Leicester Kidney Lifestyle Team

The importance of physical activity (PA) in the health and management of CKD is well established. Understanding causes of PA behaviour is essential for the development of potential interventions and promotional initiatives. We aimed to determine the prevalence and individual correlates of PA behaviour across the spectrum of kidney disease.


5258 patients across 17 geographically diverse sites were stratified into CKD stages 1-2, 3, 4-5, haemodialysis (HD), peritoneal dialysis (PD) and renal transplant recipients (RTRs). Physical activity was assessed using the GP Physical Activity Questionnaire. Potential correlates of PA included clinical, co-morbidity and demographic data, self-efficacy, stage of change (Transtheoretical Model) and cardiorespiratory fitness (VO2peak estimated using Duke Activity Status Index). Multi- and bi-nominal generalized models were used to explore differences and correlates of PA. Unless stated, data expressed as odds ratio (OR).


Prevalence of physical inactivity was high and worsened with disease progression (Fig 1). Overall, being older (OR=1.03), female (OR=1.27), having additional co-morbidities (OR=1.17), lower Hb (OR=.93) and lower VO2peak (OR=.92) were associated with being inactive. Patients in a receptive stage of change (OR=.35) and with higher self-efficacy (OR=.70) were more likely to be active. Stage of disease modified the interactions of age, sex, and VO2peak with PA.


In the largest cohort of its kind, we established that physical inactivity is highly prevalent across all stages of renal disease, reaching a nadir in those requiring dialysis and ‘recovering’ in those with a transplant. Our study emphasises the urgent need to evaluate and implement strategies that can effectively support individuals in changing their PA behaviour. In particular, approaches to promote self-efficacy may increase the likelihood that patients will engage and continue with PA.

Fig 1


  • Private Foundation Support