Kidney Week

Abstract: TH-PO621

Correlates of Physical Inactivity Across Kidney Disease Stages: An Observational Multicentre Study

Session Information

• Health Maintenance, Nutrition, Metabolism - I
  November 07, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Health Maintenance, Nutrition, and Metabolism

• 1300 Health Maintenance, Nutrition, and Metabolism

Authors

• Wilkinson, Thomas James, University of Leicester, Leicester, United Kingdom

Thomas James Wilkinson,

• Clarke, Amy Louise, University College London, London, United Kingdom

Amy Louise Clarke,

• Nixon, Daniel, University of Leicester, Leicester, United Kingdom

Daniel Nixon,

• Hull, Katherine Leigh, University Hospitals of Leicester NHS Trust, Coventry, United Kingdom

Katherine Leigh Hull,

• Burton, James, University of Leicester, Leicester, United Kingdom

James Burton,

• Smith, Alice C., University of Leicester, Leicester, United Kingdom

Alice C. Smith,

Group or Team Name

• Leicester Kidney Lifestyle Team

Background

The importance of physical activity (PA) in the health and management of CKD is well established. Understanding causes of PA behaviour is essential for the development of potential interventions and promotional initiatives. We aimed to determine the prevalence and individual correlates of PA behaviour across the spectrum of kidney disease.

Methods

5258 patients across 17 geographically diverse sites were stratified into CKD stages 1-2, 3, 4-5, haemodialysis (HD), peritoneal dialysis (PD) and renal transplant recipients (RTRs). Physical activity was assessed using the GP Physical Activity Questionnaire. Potential correlates of PA included clinical, co-morbidity and demographic data, self-efficacy, stage of change (Transtheoretical Model) and cardiorespiratory fitness (VO₂peak estimated using Duke Activity Status Index). Multi- and bi-nominal generalized models were used to explore differences and correlates of PA. Unless stated, data expressed as odds ratio (OR).

Results

Prevalence of physical inactivity was high and worsened with disease progression (Fig 1). Overall, being older (OR=1.03), female (OR=1.27), having additional co-morbidities (OR=1.17), lower Hb (OR=.93) and lower VO₂peak (OR=.92) were associated with being inactive. Patients in a receptive stage of change (OR=.35) and with higher self-efficacy (OR=.70) were more likely to be active. Stage of disease modified the interactions of age, sex, and VO₂peak with PA.

Conclusion

In the largest cohort of its kind, we established that physical inactivity is highly prevalent across all stages of renal disease, reaching a nadir in those requiring dialysis and ‘recovering’ in those with a transplant. Our study emphasises the urgent need to evaluate and implement strategies that can effectively support individuals in changing their PA behaviour. In particular, approaches to promote self-efficacy may increase the likelihood that patients will engage and continue with PA.

Fig 1

Funding

• Private Foundation Support